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Protein Overview: SHQ1

General Information:
Name(s) found: SHQ1 / YIL104C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Chaperone protein required for the assembly of box H/ACA snoRNPs and thus for pre-rRNA processing, forms a complex with Naf1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; homology with known Hsp90p cochaperones [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 507 amino acids

    Gene Ontology:
    Cellular Component: nucleoplasm [IDALink to PubMed article]
    Biological Process: snoRNA metabolic process [IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MITPRFSITQ DEEFIFLKIF ISNIRFSAVG LEIIIQENMI IFHLSPYYLR LRFPHELIDD  60
   61 ERSTAQYDSK DECINVKVAK LNKNEYFEDL DLPTKLLARQ GDLAGADALT ENTDAKKTQK 120
  121 PLIQEVETDG VSNNIKDDVK TIGQMGEGFN WEIEQKMDSS TNNGILKTKY GFDNLYDTVI 180
  181 SVSTSNGNDI NELDDPEHTD ANDRVIERLR KENLKFDPEY YVSEYMTHKY GNEEDLEING 240
  241 IKELLKFTPS IVKQYLQWYK DSTNPNLVMP IEFTDEEQKQ MQDNLPKKSY LVEDIKPLYV 300
  301 TILSVLFSYV FEQIENEGTH TTESAWTMGK LCPQISFLDQ QLKQVNELQD GMKEISKVNK 360
  361 DSSLIKIAII TGIRRALSYP LHRNYDLAMK AWTFVYYILR GGKRLVIRAL LDIHETFRFH 420
  421 DVYYVYDKVL LDDLTAWFIS QGSENVIRSL ALEMRKEQES LSKQDIEFEC IASFNEQTGE 480
  481 PEWETLNIRE MEILAESEYR EQQQNPQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2006) ALD6 PTC2 SHQ1
    View Details Ho Y, et al. (2002) CBF5 PFK2 SHQ1 SRP1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run SDO1 No Comments Hazbun TR, et al. (2003)
    View Run NSE3 No Comments Hazbun TR, et al. (2003)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SHQ1 and SPC42 Unpublished Data
    View Data SHQ1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..273] deduced N/A No confident structure predictions are available.
    2 View Details [274..507] MSA 1.007969 View MSA. No confident structure predictions are available.
    3 View Details [360..507] MSA 1.031995 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.65

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle