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Protein Overview: RHR2

General Information:
Name(s) found: RHR2 / YIL053W [SGD]
Description(s) found:
Found 13 descriptions.
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  • Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 271 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: response to drug [IMPLink to PubMed article]
    response to osmotic stress [TASLink to PubMed article]
    glycerol biosynthetic process [IMPLink to PubMed article]
    Molecular Function: glycerol-1-phosphatase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRFNVLKYI RTTKANIQTI AMPLTTKPLS LKINAALFDV DGTIIISQPA IAAFWRDFGK  60
   61 DKPYFDAEHV IHISHGWRTY DAIAKFAPDF ADEEYVNKLE GEIPEKYGEH SIEVPGAVKL 120
  121 CNALNALPKE KWAVATSGTR DMAKKWFDIL KIKRPEYFIT ANDVKQGKPH PEPYLKGRNG 180
  181 LGFPINEQDP SKSKVVVFED APAGIAAGKA AGCKIVGIAT TFDLDFLKEK GCDIIVKNHE 240
  241 SIRVGEYNAE TDEVELIFDD YLYAKDDLLK W

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run TOR2 No Comments Reinke A, et al. (2004)
    View Run VAM3 Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control). Hao Xu, et al. (2010)
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #22 Asynchronous Prep2-IMAC Phosphopeptide enrichment B1-2 Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..48]
    [101..158]
    [173..271]    		 PSI-BLAST 25.39794 Phosphoserine phosphatase
    2 View Details [49..100]
    [159..172]    		 PSI-BLAST 25.39794 Phosphoserine phosphatase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle