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Protein Overview: STP2

General Information:
Name(s) found: STP2 / YHR006W [SGD]
Description(s) found:
Found 21 descriptions.
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  • Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 541 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IPILink to PubMed article]
    Biological Process: positive regulation of transcription from RNA polymerase II promoter [IGILink to PubMed article][IMPLink to PubMed article][ISSLink to PubMed article]
    Molecular Function: specific RNA polymerase II transcription factor activity [IGILink to PubMed article][IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPILSLSSTR NSVLTRIYDY LKALVQQVIV PNVEDDKSSK STPFEKLEPA KQNHPQKDCC  60
   61 ATEKDDLVDV SELFPKQNNK QLSLTSKSSV VPCALNLDNL ETPFSIKIDN NGAVTTQLNL 120
  121 DEPILRGPSR GEPAKLQNDL ISSPPLEESY INNDQYKALF PSNFLPITPV SSVITPASKK 180
  181 SIDESPLSDE VQGIADESSE TLPYICHYCD ARFRIRGYLT RHIKKHAKRK AYHCPFFDNS 240
  241 ISQELRCHTS GGFSRRDTYK THLKSRHFTY PEGVKPQDRN KSPGVCTQCG EHFSTSESWV 300
  301 ENHIEAGSCK GLPEGYSEGI REKKKTSKMK MIKTSDGQTR FISSDESVSE PALQNKNCIE 360
  361 ATVMQSKERP NDKIIPTKTE KNDFGIGTQW FERKQISRPT QTTQSRGPTE VQNLKEWSII 420
  421 SPPILSPQNA SSVPQEYQSS RYTLHMDSPA LSSASSALSP LSGDPITTTE TNKSYPLDSE 480
  481 QSLLEPDKTE EDAINQSKES NMISINEMLQ KQMDFELLGE NHLKETQDYL ALYKKAYGIE 540
  541 F

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) LOS1 SEN15 SEN2 SEN34 SEN54 STP1 STP2 STP3 STP4 TPT1 TRL1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen RRB1 STP2 1 Unpublished Fields Lab Data
    View Screen PSF3 STP2 1 Hazbun TR, et al. (2003)
    View Screen PDS1 STP2 1 Unpublished Fields Lab Data
    View Screen YDR131C STP2 1 Unpublished Fields Lab Data
    View Screen CIA1 STP2 1 Hazbun TR, et al. (2003)
    View Screen SXM1 STP2 1 Unpublished Fields Lab Data
    View Screen YHR022C STP2 1 Unpublished Fields Lab Data
    View Screen UBC7 STP2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data STP2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..143] MSA 4.699984 View MSA. No confident structure predictions are available.
    2 View Details [144..225] PSI-BLAST 55.512579 No description for 1lu6A_ was found.
    3 View Details [226..277] PSI-BLAST 55.512579 No description for 1lu6A_ was found.
    4 View Details [278..470] PSI-BLAST 18.69897 Transcription factor IIIA, TFIIIA
    5 View Details [471..541] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

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