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Protein Overview: YLF2

General Information:
Name(s) found: YLF2 / YHL014C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Protein of unknown function, has weak similarity to E. coli GTP-binding protein gtp1; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 405 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: GTP binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIGGGKFLL GRISNNPTSG IVGLANVGKS TFFQAITNSK LGNPANYPFA TIDAECAKVN  60
   61 IPSVPLSNLL RIYQSAKCVP GTLTIYDIAG LTRGASQGHG LGNKFLNDIR HVEGIFQVVR 120
  121 GFLKEDITHI EGNVDPVRDL SVVQDELILK DLEFLENIRE RLSKKMRMVS KNSKEHQEMK 180
  181 IETELLDALE EHLFNGKKIR HFKDHWNLDE VKILNKHNFL TSKPTLILLN VSPQDYVRNE 240
  241 NKFVRNIIEW INEFSPGDKF LLFSAEFESQ LMECKGIASE YFDKIKEDTN VSDQQLVSAI 300
  301 PQIILEMRKL LNLISFFTCG PQEVHQWNIR EGTTAQEAAG VIHSDLRETF ISADVIKYDD 360
  361 LKKMEPPLNE SLLKSKGLIK RAGKQYIMQD NDIALFKAAG GKIKK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ALA1 ARO1 DUG1 GDH1 HIS4 HIS6 HRD1 MET6 OYE2 RAD14 SCP160 SPE3 SPE4 TIM11 URA6 YLF2 YRB2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YLF2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] PSI-BLAST 34.221849 GTPase Era, N-terminal domain; GTPase Era C-terminal domain
    2 View Details [203..320] PSI-BLAST 34.221849 GTPase Era, N-terminal domain; GTPase Era C-terminal domain
    3 View Details [321..405] MSA 3.111993 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle