YRC Public Data Repository - Protein Structure Prediction

Protein:	YLF2
Organism:	Saccharomyces cerevisiae
Length:	405 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLF2.

Description	E-value	Query Range	Subject Range
gi\|15075380 - gi\|15075380\|emb\|CAC46936.1\| Putative GTP-dependent nucleic acid-binding protein EngD [Sinorhizobium ... gi\|15966110 - gi\|15966110\|ref\|NP_386463.1\| translation-associated GTPase [Sinorhizobium meliloti 1021]	0.0	[15..400]	[1..367]
gi\|15157385, gi\|... - gi\|15889509\|ref\|NP_355190.1\| hypothetical protein AGR_C_4063 [Agrobacterium tumefaciens str. C58], g... gi\|25330235 - pir\|\|F97627 probable GTP-binding protein (AF107096) [imported] - Agrobacterium tumefaciens (strain C...	0.0	[15..400]	[24..390]
gi\|14042261 - gi\|14042261\|dbj\|BAB55174.1\| unnamed protein product [Homo sapiens]	0.0	[9..405]	[15..394]
OLA1_MOUSE - Obg-like ATPase 1 OS=Mus musculus GN=Ola1 PE=1 SV=1	0.0	[9..405]	[15..394]
gi\|218431822, gi... - gi\|218704725\|ref\|YP_002412244.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli U... EG11404 - catalase inhibitor protein; ATPase, K+-dependent, ribosome-associated / Catalase inhibitor protein; ... YCHF_SHIFL - Ribosome-binding ATPase YchF OS=Shigella flexneri GN=ychF PE=3 SV=2 gi\|30062727, gi\|... - gi\|30062727\|ref\|NP_836898.1\| translation-associated GTPase [Shigella flexneri 2a str. 2457T], gi\|300... YCHF_ECO57 - Ribosome-binding ATPase YchF OS=Escherichia coli O157:H7 GN=ychF PE=3 SV=2 ENGD_ECOLI - GTP-dependent nucleic acid-binding protein engD - Escherichia coli gi\|24051506, gi\|... - gi\|24112602\|ref\|NP_707112.1\| translation-associated GTPase [Shigella flexneri 2a str. 301], gi\|24051... gi\|124500646, gi... - gi\|124528414\|ref\|ZP_01699724.1\| GTP-binding protein YchF [Escherichia coli B], gi\|124500646\|gb\|EAY48... gi\|75228263, gi\|... - gi\|75228263\|ref\|ZP_00714918.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... gi\|75233900, gi\|... - gi\|75233900\|ref\|ZP_00718360.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... EG11404 - catalase inhibitor protein; ATPase, K+-dependent, ribosome-associated / Catalase inhibitor protein; ... gi\|192925613, gi... - gi\|75255061\|ref\|ZP_00726966.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... gi\|81240691, gi\|... - gi\|82776543\|ref\|YP_402892.1\| translation-associated GTPase [Shigella dysenteriae Sd197], gi\|81240691... gi\|81245754, gi\|... - gi\|82544343\|ref\|YP_408290.1\| translation-associated GTPase [Shigella boydii Sb227], gi\|81245754\|gb\|A... gi\|189356358, gi... - gi\|189356358\|gb\|EDU74777.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4401], gi\|1687... gi\|194436983, gi... - gi\|83587347\|ref\|ZP_00925975.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... gi\|168750762, gi... - gi\|188015094\|gb\|EDU53216.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4113], gi\|1687... gi\|187730029, gi... - gi\|75179198\|ref\|ZP_00699216.1\| COG0012: Predicted GTPase, probable translation factor [Shigella boyd... gi\|189360083, gi... - gi\|189360083\|gb\|EDU78502.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4486], gi\|1687... gi\|157157840, gi... - gi\|75190257\|ref\|ZP_00703524.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... gi\|168764411, gi... - gi\|189365599\|gb\|EDU84015.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4501], gi\|1687... gi\|75195356, gi\|... - gi\|75195356\|ref\|ZP_00705426.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... gi\|168782557, gi... - gi\|189000062\|gb\|EDU69048.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4076], gi\|1687... gi\|75212641, gi\|... - gi\|75212641\|ref\|ZP_00712639.1\| COG0012: Predicted GTPase, probable translation factor [Escherichia c... gi\|168777787, gi... - gi\|187767045\|gb\|EDU30889.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4196], gi\|1687... gi\|4062787, gi\|8... - gi\|89108048\|ref\|AP_001828.1\| predicted GTP-binding protein [Escherichia coli str. K-12 substr. W3110... gi\|13361173, gi\|... - gi\|15830962\|ref\|NP_309735.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli O157:... gi\|110805208, gi... - gi\|110805208\|ref\|YP_688728.1\| translation-associated GTPase [Shigella flexneri 5 str. 8401], gi\|1106... gi\|208737744, gi... - gi\|208822259\|ref\|ZP_03262578.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4042], gi\|... gi\|208733066, gi... - gi\|208816418\|ref\|ZP_03257597.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4045], gi\|... gi\|209911703, gi... - gi\|209918444\|ref\|YP_002292528.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli S... gi\|209160238, gi... - gi\|209398838\|ref\|YP_002270137.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4115], gi... gi\|238900434, gi... - gi\|238900434\|ref\|YP_002926230.1\| putative GTP-binding protein [Escherichia coli BW2952], gi\|23886245... gi\|218553757, gi... - gi\|218553757\|ref\|YP_002386670.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli I... gi\|254592073, gi... - gi\|254792673\|ref\|YP_003077510.1\| predicted GTP-binding protein [Escherichia coli O157:H7 str. TW1435... gi\|217318721, gi... - gi\|217328294\|ref\|ZP_03444376.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. TW14588], gi... gi\|218699910, gi... - gi\|218699910\|ref\|YP_002407539.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli I... gi\|218694717, gi... - gi\|218694717\|ref\|YP_002402384.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli 5... gi\|189375870, gi... - gi\|189375870\|gb\|EDU94286.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC508], gi\|16880... gi\|189372434, gi... - gi\|189372434\|gb\|EDU90850.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC869], gi\|16878... gi\|169888666, gi... - gi\|170080831\|ref\|YP_001730151.1\| GTP-binding protein [Escherichia coli str. K-12 substr. DH10B], gi\|... gi\|169755358, gi... - gi\|170020430\|ref\|YP_001725384.1\| GTP-dependent nucleic acid-binding protein EngD [Escherichia coli A... gi\|194434920, gi... - gi\|194434920\|ref\|ZP_03067165.1\| GTP-binding protein EngD [Shigella dysenteriae 1012], gi\|194416853\|g... gi\|170518703, gi... - gi\|170680985\|ref\|YP_001743991.1\| GTP-binding protein EngD [Escherichia coli SMS-3-5], gi\|170518703\|g... gi\|208806944, gi... - gi\|208806944\|ref\|ZP_03249281.1\| GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4206], gi\|... gi\|195938852 - gi\|195938852\|ref\|ZP_03084234.1\| translation-associated GTPase [Escherichia coli O157:H7 str. EC4024]	0.0	[15..400]	[1..363]
gi\|218773998, gi... - gi\|218893770\|ref\|YP_002442639.1\| GTP-dependent nucleic acid-binding protein EngD [Pseudomonas aerugi... gi\|107099660 - gi\|107099660\|ref\|ZP_01363578.1\| hypothetical protein PaerPA_01000678 [Pseudomonas aeruginosa PACS2] gi\|9950929, gi\|1... - gi\|9950929\|gb\|AAG08060.1\|AE004881_3 conserved hypothetical protein [Pseudomonas aeruginosa PAO1], gi... gi\|84317258, gi\|... - gi\|84317258\|ref\|ZP_00965709.1\| COG0012: Predicted GTPase, probable translation factor [Pseudomonas a... gi\|11348225 - pir\|\|A83061 conserved hypothetical protein PA4673 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|116052818, gi... - gi\|32039963\|ref\|ZP_00138235.1\| COG0012: Predicted GTPase, probable translation factor [Pseudomonas a...	0.0	[15..400]	[1..366]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[9..405]	[15..394]
ENGD_HAEIN - GTP-dependent nucleic acid-binding protein engD OS=Haemophilus influenzae GN=engD PE=1 SV=2 YCHF_HAEIN - Ribosome-binding ATPase YchF OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) G...	0.0	[15..400]	[1..363]

Back

Predicted Domain #1

Region A:
Residues: [1-202]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIGGGKFLL GRISNNPTSG IVGLANVGKS TFFQAITNSK LGNPANYPFA TIDAECAKVN  60
   61 IPSVPLSNLL RIYQSAKCVP GTLTIYDIAG LTRGASQGHG LGNKFLNDIR HVEGIFQVVR 120
  121 GFLKEDITHI EGNVDPVRDL SVVQDELILK DLEFLENIRE RLSKKMRMVS KNSKEHQEMK 180
  181 IETELLDALE EHLFNGKKIR HF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.221849
Match:	1egaA_
Description:	GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [203-320]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDHWNLDEVK ILNKHNFLTS KPTLILLNVS PQDYVRNENK FVRNIIEWIN EFSPGDKFLL  60
   61 FSAEFESQLM ECKGIASEYF DKIKEDTNVS DQQLVSAIPQ IILEMRKLLN LISFFTCG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.221849
Match:	1egaA_
Description:	GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [321-405]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQEVHQWNIR EGTTAQEAAG VIHSDLRETF ISADVIKYDD LKKMEPPLNE SLLKSKGLIK  60
   61 RAGKQYIMQD NDIALFKAAG GKIKK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits