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Protein Overview: ETP1

General Information:
Name(s) found: ETP1 / YHL010C [SGD]
Description(s) found:
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  • gi|731596|sp|P38748.1|YHB0_YEAST RecName: Full=RING finger protein YHL010C [NCBI NR]
  • gi|6321777|ref|NP_011853.1| Putative protein of unknown function, contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences; Yhl010cp [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S46825 hypothetical protein YHL010c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|2289881|gb|AAB65064.1| unknown [Saccharomyces cerevisiae] [NCBI NR]
  • RING finger protein YHL010C OS=Saccharomyces cerevisiae GN=YHL010C PE=1 SV=1 [Swiss-Prot]
  • RING finger protein ETP1 OS=Saccharomyces cerevisiae GN=ETP1 PE=1 SV=1 [Swiss-Prot]
  • Similarity to C.elegans hypothetical protein, homolog to human breast cancer-associated protein BRAP2 [mips]
  • Putative protein of unknown function that is required for growth on ethanol; contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences [SGD]
  • YHL010C, Chr VIII from 81959-83716, reverse complement [yeast_orfs2]
  • Chr VIII from 81959-83716, reverse complement [yeastorf3.fasta]
  • Chr VIII from 83716-81959, reverse complement [yeastorf5.fasta]
  • (P38748) Hypothetical 67.5 kDa protein in PRPS4-STE20 intergenic region [4932.FASTACCERV.txt]
  • YHL010C SGDID:S0001002, Chr VIII from 83716-81959, reverse complement, Uncharacterized ORF [yeastflysequest.fasta]
  • Yhl010cp [Saccharomyces cerevisiae]gi|2289881|gb|AAB65064.1| unknown [Saccharomyces cerevisiae]gi|731596|sp|P38748|YHB0_YEAST Hypothetical 67.5 kDa protein in PRPS4-STE20 intergenic regiongi|626567|pir||S46825 hypothetical protein YHL010c - yeast (Sacc [nrdb_11152004_Chlamydomonas]
  • YHL010C SGDID:S000001002, Chr VIII from 83717-81960, reverse complement, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YHL010C SGDID:S000001002, Chr VIII from 83717-81960, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localizat [yeast-contam.fasta]
  • Putative protein of unknown function, contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences; Yhl010cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • RING finger protein YHL010C [nr-271106-contam.fasta]
  • unknown [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • ETP1 SGDID:S000001002, Chr VIII from 83717-81960, reverse complement, Verified ORF, "Putative protein of unknown function that is required for growth on ethanol; contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta]
  • YHL010C SGDID:S000001002, Chr VIII from 83717-81960, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • ETP1 SGDID:S000001002, Chr VIII from 83717-81960, reverse complement, Verified ORF, "Putative protein of unknown function that is required for growth on ethanol; contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences" [SGDyeast.20101221.fasta]
  • RING finger protein ETP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ETP1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • ETP1 SGDID:S000001002, Chr VIII from 83721-81964, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative protein of unknown function that is required for growth on ethanol; contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences" [yeast-030211-contam.fasta]
  • ETP1 SGDID:S000001002, Chr VIII from 83721-81964, Genome Release 64-2-1, reverse complement, Verified ORF, "Putative protein of unknown function required for growth on ethanol; contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences" [20141208_orf_trans.fasta]
  • YHL010C SGDID:S000001002, Chr VIII from 83721-81964, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative protein of unknown function that is required for growth on ethanol; contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 585 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: nuclear localization sequence binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQFEYIITL EFGNQNQVES AYQIFKSIPK KLKAKSIGEE SIKSNNQDWQ DWRVCDLEID  60
   61 MITDFKNQTS KEEESDLITS QYLGHGIIRL FKLSNANNTL NEKEILTIPG DDTMICILFV 120
  121 PTYFTVHDLL HFYIGDDIVN KQVSNFRILR NQQKGMGFNF TVLIKFRNAL DAKNFKEEFN 180
  181 GKSFSRMDPE TCHVISVKEI VFQKKLFQRP AANEDFPYLL TDPFTVKKKK ELVKVELPTC 240
  241 PVCLERMDSE TTGLVTIPCQ HTFHCQCLNK WKNSRCPVCR HSSLRLSRES LLKQAGDSAH 300
  301 CATCGSTDNL WICLICGNVG CGRYNSKHAI KHYEETLHCF AMDIRTQRVW DYAGDNYVHR 360
  361 LVQNEVDGKL VEVGGSGDDD NNDIGNSDEL QNVVYGNRSK NGEKSNSNKK DGELAANFLR 420
  421 HREYHLEYVQ VLISQLESQR EYYELKLQEK DQTASDSSNV ESLKKSMEDL KLQFQVTQKE 480
  481 WQKREMAQKS KLEEDMLVIE GLQANLDHLS KKQEQLEREN KALEESKQDL EEQVKDLMFY 540
  541 LDSQEKFKDA DESVKEGTIL IQQPHGAAQA SKSKKKRNKN KKAGK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ETP1 MOH1 NHA1 YKR017C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen LSM12 ETP1 2 Unpublished Fields Lab Data
    View Screen RGT2 ETP1 1 Unpublished Fields Lab Data
    View Screen RPP0 ETP1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..209] deduced N/A No confident structure predictions are available.
    2 View Details [210..585] PSI-BLAST 21.09691 Heavy meromyosin subfragment
    3 View Details [189..585] PSI-BLAST 24.69897 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.84044925655363 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.16650337913343 bayes_pls_golite062009
  • RNA binding
    		•  1.55443392348354 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.3405047475504 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.1717600698632 bayes_pls_golite062009
  • protein binding
    		•  1.05805521997665 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.748751181289242 bayes_pls_golite062009
  • mRNA binding
    		•  0.372645027860457 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.205114038263623 bayes_pls_golite062009
  • hydrolase activity
    		•  0.181856784298799 bayes_pls_golite062009
  • protein phosphatase 2B binding
    		•  0.114018372525846 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle