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Protein Overview: ZPR1

General Information:
Name(s) found: ZPR1 / YGR211W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Essential protein with two zinc fingers, present in the nucleus of growing cells but relocates to the cytoplasm in starved cells via a process mediated by Cpr1p; binds to translation elongation factor eEF-1 (Tef1p) [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 486 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: cellular response to starvation [IMPLink to PubMed article]
    Molecular Function: protein binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEQKEDLFK PVGEAAAEVE DESIAEQNKA NDGVKLTGAQ DAMGHPVQEI ESLCMNCGKN  60
   61 GTTRLLLTSI PYFREIIIMS FDCPHCGFKN CEIQPASQIQ EKGSRYVLKV ECREDFNRQV 120
  121 IKSETATCKF VELDIEIPAK RGQLTTVEGL LSEMIDDLSQ DQEMRKSIDE ALYKKIDDFI 180
  181 QKVKSYINCE PNTIPITFIL DDPAGNSWIE YKPGEPQHKW SHTQYVRTDE QNVQVGIITR 240
  241 DQLEQRRQEQ LKQLANRERN PSESVKVGSA NPQFLSDATD IENFNNEVQT FRASCPSCTQ 300
  301 ECETHMKPVN IPHFKEVIIM STVCDHCGYK SNEVKTGGAI PDKGRRITLY CDDAADLSRD 360
  361 ILKSETCSMV IPELHLDIQE GTLGGRFTTL EGLLRQVYEE LESRIFTQTS DSMDEATKAR 420
  421 WVEFFAKLKE AIAGKVKFTV IMEDPLAGSY IQNVYAPDPD PNMTIEDYER TKEQNEDLGL 480
  481 SDIKVE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) TIR4 ZPR1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ZPR1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..256] Pfam 102.119186 ZPR1 zinc-finger domain No confident structure predictions are available.
    2 View Details [257..486] Pfam 102.79588 ZPR1 zinc-finger domain No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle