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Protein Overview: TIR4

General Information:
Name(s) found: TIR4 / YOR009W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; transcription is also induced by cold shock [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 487 amino acids

    Gene Ontology:
    Cellular Component: fungal-type cell wall [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYSKITLLA ALAAIAYAQT QAQINELNVV LDDVKTNIAD YITLSYTPNS GFSLDQMPAG  60
   61 IMDIAAQLVA NPSDDSYTTL YSEVDFSAVE HMLTMVPWYS SRLLPELEAM DASLTTSSSA 120
  121 ATSSSEVASS SIASSTSSSV APSSSEVVSS SVAPSSSEVV SSSVAPSSSE VVSSSVASSS 180
  181 SEVASSSVAP SSSEVVSSSV ASSSSEVASS SVAPSSSEVV SSSVAPSSSE VVSSSVASSS 240
  241 SEVASSSVAP SSSEVVSSSV ASSTSEATSS SAVTSSSAVS SSTESVSSSS VSSSSAVSSS 300
  301 EAVSSSPVSS VVSSSAGPAS SSVAPYNSTI ASSSSTAQTS ISTIAPYNST TTTTPASSAS 360
  361 SVIISTRNGT TVTETDNTLV TKETTVCDYS STSAVPASTT GYNNSTKVST ATICSTCKEG 420
  421 TSTATDFSTL KTTVTVCDSA CQAKKSATVV SVQSKTTGIV EQTENGAAKA VIGMGAGALA 480
  481 AVAAMLL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) TIR4 ZPR1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..123] Pfam 36.823909 Seripauperin and TIP1 family No confident structure predictions are available.
    2 View Details [124..423] ORFEUS 12.03 Fibrinogen
    3 View Details [424..487] ORFEUS 12.23 Fibrinogen
    4 View Details [385..487] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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