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Protein Overview: PMT6

General Information:
Name(s) found: PMT6 / YGR199W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Protein O-mannosyltransferase, transfers mannose from dolichyl phosphate-D-mannose to protein serine/threonine residues of secretory proteins; reaction is essential for cell wall rigidity; member of a family of mannosyltransferases [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 759 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [TASLink to PubMed article]
    Biological Process: protein amino acid O-linked glycosylation [TASLink to PubMed article]
    Molecular Function: dolichyl-phosphate-mannose-protein mannosyltransferase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKAKGTGFS SIDTEDENLR ERYVNQPKAN ASDIQDEQLD CFEQLEEKHR TKKNEEYTAL  60
   61 KILRDVIGPL LLTITSFYLR FQHIDQNNYV VWDEAHFGKF GSYYIKHEYY HDVHPPLGKM 120
  121 LIALSEWMAG FDGQFDFSSN NAYPENVNFK LMRQFNATFG ALCTPVAFFT AKWMGFNYFT 180
  181 VYLIATMVTL EHSYIVLSKF ILLDSMLLFF SMTTFACMIK LYTLRKQQMT KKWSLWMLLT 240
  241 GLSIGCVCSV KWVGLFITVV VGLYTCIELF LLYCDKELPR IKYYKHWLIR IINLIVIPFL 300
  301 IYLYCFKIHF VLLYKSGTGD STTNTLFQIN LEGTQIEAGP RDVAFGSELT IRSHGLSPNL 360
  361 LHSHIQVYPE GSGQRQITGY GFADSNNVWK FEFSRSSGLE LDQNGTLNGK IIPITDGVEV 420
  421 RLSHKNTGSN LHSHDVPSHV SRGNYEVSGY GSQSVGDEKD DWIVEIVKQM DSPNPVYSNE 480
  481 NSTILHPVST FFRLRHKVLG CYLASTGLTY PAWGFKQAEI VCKDSWSRRD KSTWWNVEDH 540
  541 WNHNLETAED YVPPKSNFWT DFILTNFAMA SSNNALVPDE DKYDSLSSDA WEWPTLHKGL 600
  601 RMCSWAGYIT RYYLMGSPFN TWISTVSLII FPFIILFILY RWRRQTLYLS DDQIWQITIQ 660
  661 GIFPFISWMT HYLPFAMMGR VTYVHHYVPA LYFAMLVFGF VLDFTLTRVH WMVKYPIYLS 720
  721 LFGGCIYIYN LFAPICQGMH GDKAEYLPLQ WLSTWDIAP

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) PMT2 PMT3 PMT6

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..337] Pfam 100.366532 Dolichyl-phosphate-mannose-protein mannosyltransferase No confident structure predictions are available.
    2 View Details [338..400] Pfam 13.60206 MIR domain No confident structure predictions are available.
    3 View Details [401..538] ORFEUS 11.09 IP3 receptor type 1 binding core, domain 2; IP3 receptor type 1 binding core, domain 1
    4 View Details [539..759] MSA 5.036965 View MSA. No confident structure predictions are available.
    5 View Details [648..759] MSA 2.088972 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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