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Protein Overview: PCP1

General Information:
Name(s) found: PCP1 / YGR101W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Mitochondrial serine protease required for the processing of various mitochondrial proteins and maintenance of mitochondrial DNA and morphology; belongs to the rhomboid-GlpG superfamily of intramembrane peptidases [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 346 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [TASLink to PubMed article]
    Biological Process: protein import into mitochondrial intermembrane space [TASLink to PubMed article]
    telomere maintenance [IMPLink to PubMed article]
    signal peptide processing [IMPLink to PubMed article]
    mitochondrion organization [IMPLink to PubMed article]
    Molecular Function: peptidase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGVSSVMLG LRPATRIFFR SNISVSPSRT FVSYIGRSQS TSILKNAPNL EDNVTNLQKI  60
   61 IPKRFFSQTS ILKSRWKPIF NEETTNRYVR LNRFQQYQQQ RSGGNPLGSM TILGLSLMAG 120
  121 IYFGSPYLFE HVPPFTYFKT HPKNLVYALL GINVAVFGLW QLPKCWRFLQ KYMLLQKDYV 180
  181 TSKISIIGSA FSHQEFWHLG MNMLALWSFG TSLATMLGAS NFFSLYMNSA IAGSLFSLWY 240
  241 PKLARLAIVG PSLGASGALF GVLGCFSYLF PHAKILLFVF PVPGGAWVAF LASVAWNAAG 300
  301 CALRWGSFDY AAHLGGSMMG VLYGWYISKA VEKQRQRRLQ AAGRWF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PCP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..104] deduced N/A No confident structure predictions are available.
    2 View Details [105..346] Pfam 51.443697 Rhomboid family No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle