YRC Public Data Repository - Protein Structure Prediction

Protein:	PCP1
Organism:	Saccharomyces cerevisiae
Length:	346 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PCP1.

Description	E-value	Query Range	Subject Range
PCP1 - Mitochondrial serine protease required for the processing of various mitochondrial proteins and main... gi\|190406879 - gi\|190406879\|gb\|EDV10146.1\| rhomboid protease [Saccharomyces cerevisiae RM11-1a] PCP1_YEAST - Rhomboid protein 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PCP1 P... gi\|151943378 - gi\|151943378\|gb\|EDN61691.1\| rhomboid protease [Saccharomyces cerevisiae YJM789]	1.0E-81	[1..346]	[1..346]
gi\|17431999 - gi\|17431999\|emb\|CAD18676.1\| probable membrane transmembrane protein [Ralstonia solanacearum GMI1000] gi\|17549744 - gi\|17549744\|ref\|NP_523084.1\| hypothetical protein RS04802 [Ralstonia solanacearum GMI1000]	3.0E-50	[37..341]	[110..404]
gi\|220952854 - gi\|220952854\|gb\|ACL88970.1\| ru-PA [synthetic construct] ru-PA - The gene roughoid is referred to in FlyBase by the symbol Dmel\ru (CG1214, FBgn0003295). It is a pro...	3.0E-41	[43..345]	[3..301]
GLUP_BACSU, YQGP... - TPR repeat-containing protein yqgP - Bacillus subtilis, Rhomboid protease gluP OS=Bacillus subtilis ... gi\|16079543, gi\|... - gi\|2634921\|emb\|CAB14418.1\| yqgP [Bacillus subtilis subsp. subtilis str. 168], gi\|16079543\|ref\|NP_390...	3.0E-40	[59..340]	[97..365]
RBL3_ARATH - RHOMBOID-like protein 3 OS=Arabidopsis thaliana GN=RBL3 PE=2 SV=1	3.0E-37	[88..338]	[9..278]
gi\|18145114, gi\|... - gi\|18310434\|ref\|NP_562368.1\| rhomboid family protein [Clostridium perfringens str. 13], gi\|18145114\|...	8.0E-37	[97..330]	[105..337]
gi\|123993533, gi... - gi\|124000479\|gb\|ABM87748.1\| presenilin associated, rhomboid-like [synthetic construct], gi\|123993533... PARL - presenilin associated, rhomboid-like	1.0E-36	[146..336]	[169..358]
gi\|25489851 - pir\|\|E83827 hypothetical protein BH1421 [imported] - Bacillus halodurans (strain C-125) gi\|15613984, gi\|... - gi\|15613984\|ref\|NP_242287.1\| hypothetical protein BH1421 [Bacillus halodurans C-125], gi\|10174038\|db...	2.0E-35	[119..339]	[171..374]

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Predicted Domain #1

Region A:
Residues: [1-104]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGVSSVMLG LRPATRIFFR SNISVSPSRT FVSYIGRSQS TSILKNAPNL EDNVTNLQKI  60
   61 IPKRFFSQTS ILKSRWKPIF NEETTNRYVR LNRFQQYQQQ RSGG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [105-346]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPLGSMTILG LSLMAGIYFG SPYLFEHVPP FTYFKTHPKN LVYALLGINV AVFGLWQLPK  60
   61 CWRFLQKYML LQKDYVTSKI SIIGSAFSHQ EFWHLGMNML ALWSFGTSLA TMLGASNFFS 120
  121 LYMNSAIAGS LFSLWYPKLA RLAIVGPSLG ASGALFGVLG CFSYLFPHAK ILLFVFPVPG 180
  181 GAWVAFLASV AWNAAGCALR WGSFDYAAHL GGSMMGVLYG WYISKAVEKQ RQRRLQAAGR 240
  241 WF

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	51.443697
Match:	PF01694
Description:	Rhomboid family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits