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View Structure Prediction Details

Protein: PCP1
Organism: Saccharomyces cerevisiae
Length: 346 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PCP1.

Description E-value Query
Range
Subject
Range
PCP1 - Mitochondrial serine protease required for the processing of various mitochondrial proteins and main...
gi|190406879 - gi|190406879|gb|EDV10146.1| rhomboid protease [Saccharomyces cerevisiae RM11-1a]
PCP1_YEAST - Rhomboid protein 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PCP1 P...
gi|151943378 - gi|151943378|gb|EDN61691.1| rhomboid protease [Saccharomyces cerevisiae YJM789]
1.0E-81 [1..346] [1..346]
gi|17431999 - gi|17431999|emb|CAD18676.1| probable membrane transmembrane protein [Ralstonia solanacearum GMI1000]
gi|17549744 - gi|17549744|ref|NP_523084.1| hypothetical protein RS04802 [Ralstonia solanacearum GMI1000]
3.0E-50 [37..341] [110..404]
gi|220952854 - gi|220952854|gb|ACL88970.1| ru-PA [synthetic construct]
ru-PA - The gene roughoid is referred to in FlyBase by the symbol Dmel\ru (CG1214, FBgn0003295). It is a pro...
3.0E-41 [43..345] [3..301]
GLUP_BACSU, YQGP... - TPR repeat-containing protein yqgP - Bacillus subtilis, Rhomboid protease gluP OS=Bacillus subtilis ...
gi|16079543, gi|... - gi|2634921|emb|CAB14418.1| yqgP [Bacillus subtilis subsp. subtilis str. 168], gi|16079543|ref|NP_390...
3.0E-40 [59..340] [97..365]
RBL3_ARATH - RHOMBOID-like protein 3 OS=Arabidopsis thaliana GN=RBL3 PE=2 SV=1
3.0E-37 [88..338] [9..278]
gi|18145114, gi|... - gi|18310434|ref|NP_562368.1| rhomboid family protein [Clostridium perfringens str. 13], gi|18145114|...
8.0E-37 [97..330] [105..337]
gi|123993533, gi... - gi|124000479|gb|ABM87748.1| presenilin associated, rhomboid-like [synthetic construct], gi|123993533...
PARL - presenilin associated, rhomboid-like
1.0E-36 [146..336] [169..358]
gi|25489851 - pir||E83827 hypothetical protein BH1421 [imported] - Bacillus halodurans (strain C-125)
gi|15613984, gi|... - gi|15613984|ref|NP_242287.1| hypothetical protein BH1421 [Bacillus halodurans C-125], gi|10174038|db...
2.0E-35 [119..339] [171..374]

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Predicted Domain #1
Region A:
Residues: [1-104]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGVSSVMLG LRPATRIFFR SNISVSPSRT FVSYIGRSQS TSILKNAPNL EDNVTNLQKI  60
   61 IPKRFFSQTS ILKSRWKPIF NEETTNRYVR LNRFQQYQQQ RSGG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.432 a.22.1 Histone-fold
View Download 0.432 a.22.1 Histone-fold
View Download 0.283 a.77.1 DEATH domain
View Download 0.283 a.77.1 DEATH domain
View Download 0.649 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.649 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.319 a.4.12 TrpR-like
View Download 0.319 a.4.12 TrpR-like
View Download 0.290 a.60.8 HRDC-like
View Download 0.290 a.60.8 HRDC-like
View Download 0.265 a.29.2 Bromodomain
View Download 0.256 c.30.1 PreATP-grasp domain
View Download 0.229 a.77.1 DEATH domain
View Download 0.224 a.2.7 tRNA-binding arm
View Download 0.219 a.74.1 Cyclin-like
View Download 0.219 a.77.1 DEATH domain
View Download 0.217 a.29.2 Bromodomain
View Download 0.210 a.60.13 Putative methyltransferase TM0872, insert domain
View Download 0.201 a.71.2 Helical domain of Sec23/24

Predicted Domain #2
Region A:
Residues: [105-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPLGSMTILG LSLMAGIYFG SPYLFEHVPP FTYFKTHPKN LVYALLGINV AVFGLWQLPK  60
   61 CWRFLQKYML LQKDYVTSKI SIIGSAFSHQ EFWHLGMNML ALWSFGTSLA TMLGASNFFS 120
  121 LYMNSAIAGS LFSLWYPKLA RLAIVGPSLG ASGALFGVLG CFSYLFPHAK ILLFVFPVPG 180
  181 GAWVAFLASV AWNAAGCALR WGSFDYAAHL GGSMMGVLYG WYISKAVEKQ RQRRLQAAGR 240
  241 WF

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 51.443697
Match: PF01694
Description: Rhomboid family

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle