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Protein Overview: ARI1

General Information:
Name(s) found: ARI1 / YGL157W [SGD]
Description(s) found:
Found 23 descriptions.
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  • NADPH-dependent aldehyde reductase, utilizes aromatic and alophatic aldehyde substrates; member of the short-chain dehydrogenase/reductase superfamily [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 347 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: oxidoreductase activity [IDALink to PubMed article]
    dihydrokaempferol 4-reductase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTDTTVFVS GATGFIALHI MNDLLKAGYT VIGSGRSQEK NDGLLKKFNN NPKLSMEIVE  60
   61 DIAAPNAFDE VFKKHGKEIK IVLHTASPFH FETTNFEKDL LTPAVNGTKS ILEAIKKYAA 120
  121 DTVEKVIVTS STAALVTPTD MNKGDLVITE ESWNKDTWDS CQANAVAAYC GSKKFAEKTA 180
  181 WEFLKENKSS VKFTLSTINP GFVFGPQMFA DSLKHGINTS SGIVSELIHS KVGGEFYNYC 240
  241 GPFIDVRDVS KAHLVAIEKP ECTGQRLVLS EGLFCCQEIV DILNEEFPQL KGKIATGEPA 300
  301 TGPSFLEKNS CKFDNSKTKK LLGFQFYNLK DCIVDTAAQM LEVQNEA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ARI1 POL4 ROK1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ARI1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88]
    [99..130]
    [173..198]
    [249..265]    		 PSI-BLAST 102.0 dTDP-glucose 4,6-dehydratase (RmlB)
    2 View Details [89..98]
    [131..172]
    [199..209]
    [238..248]
    [266..276]
    [304..334]    		 PSI-BLAST 102.0 dTDP-glucose 4,6-dehydratase (RmlB)
    3 View Details [210..237]
    [277..303]
    [335..347]    		 PSI-BLAST 102.0 dTDP-glucose 4,6-dehydratase (RmlB)


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle