Protein Overview: YFL040W

General Information:
Name(s) found:	YFL040W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|836715\|dbj\|BAA09200.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] gi\|1589357\|prf\|\|2210408B ORF 4121orfR004 [NCBI NR] gi\|14318478\|ref\|NP_116613.1\| Putative transporter, member of the sugar porter family; YFL040W is not an essential gene; Yfl040wp [Saccharomyces cerevisiae] [NCBI NR] gi\|1175946\|sp\|P43562.1\|YFE0_YEAST RecName: Full=Probable metabolite transport protein YFL040W [NCBI NR] pir\|\|S56215 probable membrane protein YFL040w - yeast (Saccharomyces cerevisiae) [NCBI NR] Probable metabolite transport protein YFL040W OS=Saccharomyces cerevisiae GN=YFL040W PE=1 SV=1 [Swiss-Prot] Similarity to yeast glucose transport proteins [mips] Putative transporter, member of the sugar porter family; YFL040W is not an essential gene [SGD] YFL040W, Chr VI from 51350-52972 [yeast_orfs2] Chr VI from 51350-52972 [yeastorf3.fasta] (P43562) Probable metabolite transport protein YFL040W [4932.FASTACCERV.txt] YFL040W SGDID:S0001854, Chr VI from 51350-52972, Uncharacterized ORF [yeastflysequest.fasta] Yfl040wp [Saccharomyces cerevisiae]gi\|1175946\|sp\|P43562\|YFE0_YEAST Probable metabolite transport protein YFL040Wgi\|1084699\|pir\|\|S56215 probable membrane protein YFL040w - yeast (Saccharomyces cerevisiae)gi\|836715\|dbj\|BAA09200.1\| YFL040W [Saccharomyces [nrdb_11152004_Chlamydomonas] YFL040W SGDID:S000001854, Chr VI from 51350-52972, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YFL040W SGDID:S000001854, Chr VI from 51350-52972, Uncharacterized ORF, "Putative protein of unknown function; YFL040W is not an essential gene" [yeast-contam.fasta] YFL040W SGDID:S000001854, Chr VI from 51350-52972, Uncharacterized ORF, "Putative transporter, member of the sugar porter family; YFL040W is not an essential gene" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] ORF 4121orfR004 [nr-271106-contam.fasta] Putative protein of unknown function; YFL040W is not an essential gene; Yfl040wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Probable metabolite transport protein YFL040W [nr-271106-contam.fasta] [chemostatdb.fasta] Probable metabolite transport protein YFL040W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YFL040W PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] YFL040W SGDID:S000001854, Chr VI from 51350-52972, Genome Release 64-1-1, Uncharacterized ORF, "Putative transporter, member of the sugar porter family; YFL040W is not an essential gene" [yeast-030211-contam.fasta] YFL040W SGDID:S000001854, Chr VI from 51350-52972, Genome Release 64-2-1, Uncharacterized ORF, "Putative transporter; member of the sugar porter family; YFL040W is not an essential gene" [20141208_orf_trans.fasta]
Organism:	Saccharomyces cerevisiae
Length:	540 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAMKAIVWR LPKMPKIKIT KTYEVTKITA ILTLVGFIMG LEVPSLATFL TNKTFNEYFK  60
   61 YPTPLQQGLL MGSTPLGGIM GCFICCIMND RFSRIYQFQS GIIIWNIVTL LNFCIWDILG 120
  121 LLICRMIKGM ILGNFSILVA SYANEVIPRG KRGSTMSYIQ LCLTIGILVM HYLCIALSLW 180
  181 DSHFAFRIAW CIGIIPGLLF WMASYALPES YHWLVLHGKM SEAQEIQHNL AKKFNESQPR 240
  241 DAVPEMSKIE LAGDFWIGVN DLDFSKKLPR GSFKPLILGM TLQLLVQFSG INIILGYITY 300
  301 ICEIVGLEGN VKLFTSSIPY FINMVLSLLP ITFIDYTSRK LITLLGGFPI SGLLITIGAL 360
  361 FVKYGQDTKP IDGNRSLVWS IGENPFVGGW ILTLCFLIVG IFAMSLSSIP WVYTNEMLPS 420
  421 RVKVKGFAIC VTFGWLGNFI LTFLCPVMIE RLKGTTFIIF GSLTFLISLS VLIWFPETKG 480
  481 MSIEDIDKFF EFESKEGTNL HGEKGIKTPD SNSNGGSTRS SQEGQLHKPI KLKSDEEMII 540
  541

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	RPN9	YFL040W	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..208] [259..479]	PSI-BLAST	237.9897	No description for 1ja5A_ was found.
2	View Details	[209..258] [480..540]	PSI-BLAST	237.9897	No description for 1ja5A_ was found.

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
glycerol transmembrane transporter activity	7.11654923455995	bayes_pls_golite062009
alcohol transmembrane transporter activity	6.7545566917184	bayes_pls_golite062009
polyol transmembrane transporter activity	6.7545566917184	bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity	5.74077413704789	bayes_pls_golite062009
transporter activity	4.09176719149278	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.54194478414824	bayes_pls_golite062009
hexose phosphate transmembrane transporter activity	3.3746965264994	bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity	3.3746965264994	bayes_pls_golite062009
sugar:hydrogen symporter activity	2.99050613058546	bayes_pls_golite062009
cation:sugar symporter activity	2.99050613058546	bayes_pls_golite062009
monosaccharide transmembrane transporter activity	2.63293544825311	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	2.62141276633776	bayes_pls_golite062009
sugar transmembrane transporter activity	2.47557586092261	bayes_pls_golite062009
ion transmembrane transporter activity	2.21266150105753	bayes_pls_golite062009
solute:hydrogen symporter activity	2.10485633822652	bayes_pls_golite062009
cation transmembrane transporter activity	1.79369588808394	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
binding	1.46605775041083	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
sugar binding	0.285073104957756	bayes_pls_golite062009

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2