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Protein Overview: CAJ1

General Information:
Name(s) found: CAJ1 / YER048C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Nuclear type II J heat shock protein of the E. coli dnaJ family, contains a leucine zipper-like motif, binds to non-native substrates for presentation to Ssa3p, may function during protein translocation, assembly and disassembly [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 391 amino acids

    Gene Ontology:
    Cellular Component: nucleus [TASLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: chaperone regulator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKETEYYDI LGIKPEATPT EIKKAYRRKA METHPDKHPD DPDAQAKFQA VGEAYQVLSD  60
   61 PGLRSKYDQF GKEDAVPQQG FEDASEYFTA IFGGDGFKDW IGEFSLFKEL NEATEMFGKE 120
  121 DEEGTAATET EKADESTDGG MVKHDTNKAE SLKKDKLSKE QREKLMEMEK KRREDMMKQV 180
  181 DELAEKLNEK ISRYLIAVKS NNLEEFTRKL DQEIEDLKLE SFGLELLYLL ARVYKTKANN 240
  241 FIMSKKTYGI SKIFTGTRDN ARSVKSAYNL LSTGLEAQKA MEKMSEVNTD ELDQYERAKF 300
  301 ESTMAGKALG VMWAMSKFEL ERKLKDVCNK ILNDKKVPSK ERIAKAKAML FIAHKFASAR 360
  361 RSPEEAEEAR VFEELILGEQ EKEHKKHTVA R

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ARC15 ASR1 CAJ1 CDC7 CRN1 INP52 IRC22 MSK1 PNO1 PST2 RAD34 SAC6 SAR1 SLM1 TCP1 TED1 YPP1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CAJ1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..144] PSI-BLAST 137.69897 NMR STRUCTURE OF THE J-DOMAIN (RESIDUES 2-76) IN THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 2-108) OF THE MOLECULAR CHAPERONE DNAJ, 20 STRUCTURES
    2 View Details [145..287] PSI-BLAST 4.221849 Heat shock protein 40 Sis1
    3 View Details [288..391] MSA 1.042991 View MSA. Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle