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Protein Overview: CIN8

General Information:
Name(s) found: CIN8 / YEL061C [SGD]
Description(s) found:
Found 10 descriptions.
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  • Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1038 amino acids

    Gene Ontology:
    Cellular Component: spindle microtubule [IDALink to PubMed article][TASLink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    condensed nuclear chromosome kinetochore [IDALink to PubMed article]
    kinesin complex [TASLink to PubMed article]
    Biological Process: mitotic sister chromatid segregation [TASLink to PubMed article]
    mitotic anaphase B [IMPLink to PubMed article]
    mitotic spindle organization in nucleus [TASLink to PubMed article]
    Molecular Function: microtubule motor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVWPESNVEY RYRSKQFKGK SNKKYIKAQK IQQERICLMP AENQNTGQDR SSNSISKNGN  60
   61 SQVGCHTVPN EELNITVAVR CRGRNEREIS MKSSVVVNVP DITGSKEISI NTTGDTGITA 120
  121 QMNAKRYTVD KVFGPGASQD LIFDEVAGPL FQDFIKGYNC TVLVYGMTST GKTYTMTGDE 180
  181 KLYNGELSDA AGIIPRVLLK LFDTLELQQN DYVVKCSFIE LYNEELKDLL DSNSNGSSNT 240
  241 GFDGQFMKKL RIFDSSTANN TTSNSASSSR SNSRNSSPRS LNDLTPKAAL LRKRLRTKSL 300
  301 PNTIKQQYQQ QQAVNSRNNS SSNSGSTTNN ASSNTNTNNG QRSSMAPNDQ TNGIYIQNLQ 360
  361 EFHITNAMEG LNLLQKGLKH RQVASTKMND FSSRSHTIFT ITLYKKHQDE LFRISKMNLV 420
  421 DLAGSENINR SGALNQRAKE AGSINQSLLT LGRVINALVD KSGHIPFRES KLTRLLQDSL 480
  481 GGNTKTALIA TISPAKVTSE ETCSTLEYAS KAKNIKNKPQ LGSFIMKDIL VKNITMELAK 540
  541 IKSDLLSTKS KEGIYMSQDH YKNLNSDLES YKNEVQECKR EIESLTSKNA LLVKDKLKSK 600
  601 ETIQSQNCQI ESLKTTIDHL RAQLDKQHKT EIEISDFNNK LQKLTEVMQM ALHDYKKREL 660
  661 DLNQKFEMHI TKEIKKLKST LFLQLNTMQQ ESILQETNIQ PNLDMIKNEV LTLMRTMQEK 720
  721 AELMYKDCVK KILNESPKFF NVVIEKIDII RVDFQKFYKN IAENLSDISE ENNNMKQYLK 780
  781 NHFFKNNHQE LLNRHVDSTY ENIEKRTNEF VENFKKVLND HLDENKKLIM QNLTTATSAV 840
  841 IDQEMDLFEP KRVKWENSFD LINDCDSMNN EFYNSMAATL SQIKSTVDTS SNSMNESISV 900
  901 MKGQVEESEN AISLLKNNTK FNDQFEQLIN KHNMLKDNIK NSITSTHSHI TNVDDIYNTI 960
  961 ENIMKNYGNK ENATKDEMIE NILKEIPNLS KKMPLRLSNI NSNSVQSVIS PKKHAIEDEN1020
 1021 KSSENVDNEG SRKMLKIE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..64] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [65..184] MSA 4.168996 View MSA. No confident structure predictions are available.
    3 View Details [185..547] PSI-BLAST 586.491979 Kinesin
    4 View Details [548..735] deduced N/A No confident structure predictions are available.
    5 View Details [736..1038] PSI-BLAST 11.30103 Heavy meromyosin subfragment


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle