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View Structure Prediction Details

Protein: CIN8
Organism: Saccharomyces cerevisiae
Length: 1038 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CIN8.

Description E-value Query
Range
Subject
Range
gi|3542, gi|171225 - gi|3542|emb|CAA77885.1| Cin8p [Saccharomyces cerevisiae], gi|171225|gb|AAA34496.1| kinesin-related p...
0.0 [1..1038] [1..1038]
gi|4512330 - gi|4512330|dbj|BAA75243.1| KIF1B-beta [Mus musculus]
0.0 [153..959] [5..829]
KIF1B - kinesin family member 1B
0.0 [153..956] [5..872]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [153..1032] [5..869]
gi|8248421 - gi|8248421|gb|AAF74192.1|AF247761_1 kinesin superfamily member DUnc104 [Drosophila melanogaster]
0.0 [176..945] [28..826]

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Predicted Domain #1
Region A:
Residues: [1-64]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVWPESNVEY RYRSKQFKGK SNKKYIKAQK IQQERICLMP AENQNTGQDR SSNSISKNGN  60
   61 SQVG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.955 0.048 mitotic spindle organization in nucleus b.84.2 Rudiment single hybrid motif

Predicted Domain #2
Region A:
Residues: [65-184]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CHTVPNEELN ITVAVRCRGR NEREISMKSS VVVNVPDITG SKEISINTTG DTGITAQMNA  60
   61 KRYTVDKVFG PGASQDLIFD EVAGPLFQDF IKGYNCTVLV YGMTSTGKTY TMTGDEKLYN 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [185-547]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GELSDAAGII PRVLLKLFDT LELQQNDYVV KCSFIELYNE ELKDLLDSNS NGSSNTGFDG  60
   61 QFMKKLRIFD SSTANNTTSN SASSSRSNSR NSSPRSLNDL TPKAALLRKR LRTKSLPNTI 120
  121 KQQYQQQQAV NSRNNSSSNS GSTTNNASSN TNTNNGQRSS MAPNDQTNGI YIQNLQEFHI 180
  181 TNAMEGLNLL QKGLKHRQVA STKMNDFSSR SHTIFTITLY KKHQDELFRI SKMNLVDLAG 240
  241 SENINRSGAL NQRAKEAGSI NQSLLTLGRV INALVDKSGH IPFRESKLTR LLQDSLGGNT 300
  301 KTALIATISP AKVTSEETCS TLEYASKAKN IKNKPQLGSF IMKDILVKNI TMELAKIKSD 360
  361 LLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 586.491979
Match: 1ii6A_
Description: Kinesin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [548-735]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKSKEGIYMS QDHYKNLNSD LESYKNEVQE CKREIESLTS KNALLVKDKL KSKETIQSQN  60
   61 CQIESLKTTI DHLRAQLDKQ HKTEIEISDF NNKLQKLTEV MQMALHDYKK RELDLNQKFE 120
  121 MHITKEIKKL KSTLFLQLNT MQQESILQET NIQPNLDMIK NEVLTLMRTM QEKAELMYKD 180
  181 CVKKILNE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [736-1038]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPKFFNVVIE KIDIIRVDFQ KFYKNIAENL SDISEENNNM KQYLKNHFFK NNHQELLNRH  60
   61 VDSTYENIEK RTNEFVENFK KVLNDHLDEN KKLIMQNLTT ATSAVIDQEM DLFEPKRVKW 120
  121 ENSFDLINDC DSMNNEFYNS MAATLSQIKS TVDTSSNSMN ESISVMKGQV EESENAISLL 180
  181 KNNTKFNDQF EQLINKHNML KDNIKNSITS THSHITNVDD IYNTIENIMK NYGNKENATK 240
  241 DEMIENILKE IPNLSKKMPL RLSNINSNSV QSVISPKKHA IEDENKSSEN VDNEGSRKML 300
  301 KIE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.30103
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle