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Protein Overview: PSP1

General Information:
Name(s) found: PSP1 / YDR505C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Asn and gln rich protein of unknown function; high-copy suppressor of POL1 (DNA polymerase alpha) and partial suppressor of CDC2 (polymerase delta) and CDC6 (pre-RC loading factor) mutations; overexpression results in growth inhibition [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 841 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLPTVNSTT SISDNVDLKN YYEDLLFKNN SGKSLSDLPR KLNDNSNNSG SDTVDPLAGL  60
   61 NNLRNSIKSA GNGMENRRTF DDIDFMGRFP YLPPVPNQQQ QPFSHQNGFI QEHPSSNLTS 120
  121 FQMSSSNSEP MSAPPISSNN NNLNSTQMGN YQAQQRSFPQ FNGNSFHSNG NDLMGNRMDS 180
  181 DYMRLMNKTN IGFTSNSGSN FAAPSHSAGN PSSMNNQQVP SFNWQQPSHP ESTIRRSSYI 240
  241 SDTLINHQMP DARQKQTSQV QQQHAQGFNL FNSRFNYDNL NSTHLTAKGV PEFGNGVQPP 300
  301 YPYDNEPNNA SISNSNNNNN SHNMVPMQQF RRNTQPVASF NPSLPTFQQQ QQQPQQPQQP 360
  361 RNVNVPTSFN GERVDDVQLV QLQRSSSVPS STNSHNLQNE NSNEGNVSLD NGLVLIQGKH 420
  421 LTSSKTLHDL YSDCGSGYFA SSAVFEFTDN IKKMLKLHDS NESYDAKNMG LIDEEGNTYQ 480
  481 SLLNFLDILR SCNMNYVNDP ESNNGIVSNN GGNKNRRKGS FTTELSCRNA NNSFLPYTPL 540
  541 VLVALKNGKL ELLSTPQATN LLLKRGDLVI IDGDRGRDLV LVVEPSVDLN LALFINFLKK 600
  601 KIHFDSLITS ESQHYRNDEF IQMLIDSKNG QKKKLNPKLY DVVELTELII PSKQVLRFAT 660
  661 PWEVTTNLHN KFEDELKALH IAQSKLQALN DNSKSQNTND SSSNNFTNAA TYSKPKLNIK 720
  721 ILNAEFQFDR KELTFYYVCE ERNDFRDLIK ELFKYYKTRI WLCAIPNNLS IDSKYYDKQQ 780
  781 KELKLYQNIV KNYNAEDLMN VNEFSQNRGN NRVNFAPPLN EIELDNFQIA VYEELVHELF 840
  841 H

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run NOP9 No Comments Hazbun TR, et al. (2003)
    View Run CLB2 No Comments McCusker D, et al (2007)
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PSP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..178] deduced N/A No confident structure predictions are available.
    2 View Details [179..248]
    [353..387]
    [419..491]
    [528..559]    		 ORFEUS 7.13 Adenovirus hexon
    3 View Details [249..352]
    [388..418]
    [492..527]
    [560..614]    		 ORFEUS 7.13 Adenovirus hexon
    4 View Details [615..841] ORFEUS 7.88 RNA-polymerase beta-prime
    5 View Details [630..841] Pfam 16.568636 No description for PF04468.3 was found. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle