YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: HRQ1

General Information:
Name(s) found: HRQ1 / YDR291W [SGD]
Description(s) found:
Found 28 descriptions.
SHOW ALL
  • Putative RecQ helicase; belongs to the widely conserved RecQ family of proteins which are involved in maintaining genomic integrity; similar to the human RecQ4p implicated in Rothmund-Thomson syndrome(RTS) [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1077 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEGPIKKKL KSAGQGSGKT DAFRNFEQFF FRLNTLYTFL ICRKHVVPTF KTLCGPIETA  60
   61 LKRTVTKEDL AMVMALMPRE CVFKYIDENQ IYTETKIFDF NNGGFQQKEN DIFELKDVDD 120
  121 QNQTQKSTQL LIFEFIDGTM QRSWSASDRF SQIKIPTYTT EEMKKMISKR EALFKSRLRE 180
  181 FILEKEKANL DPFSELTNLA QKYIPRERDY EDPIEAMMKA KQESNEMSIP NYSNNSVITT 240
  241 IPQMIEKLKS TEFYASQIKH CFTIPSRTAK YKGLCFELAP EVYQGMEHEN FYSHQADAIN 300
  301 SLHQGENVII TTSTSSGKSL IYQLAAIDLL LKDPESTFMY IFPTKALAQD QKRAFKVILS 360
  361 KIPELKNAVV DTYDGDTEPE ERAYIRKNAR VIFTNPDMIH TSILPNHANW RHFLYHLKLV 420
  421 VVDELHIYKG LFGSHVALVM RRLLRLCHCF YENSGLQFIS CSATLKSPVQ HMKDMFGINE 480
  481 VTLIHEDGSP TGAKHLVVWN PPILPQHERK RENFIRESAK ILVQLILNNV RTIAFCYVRR 540
  541 VCELLMKEVR NIFIETGRED LVTEVMSYRG GYSASDRRKI EREMFHGNLK AVISTNALEL 600
  601 GIDIGGLDAV LMCGFPLSMA NFHQQSGRAG RRNNDSLTLV VASDSPVDQH YVAHPESLLE 660
  661 VNNFESYQDL VLDFNNILIL EGHIQCAAFE LPINFERDKQ YFTESHLRKI CVERLHHNQD 720
  721 GYHASNRFLP WPSKCVSLRG GEEDQFAVVD ITNGRNIIIE EIEASRTSFT LYDGGIFIHQ 780
  781 GYPYLVKEFN PDERYAKVQR VDVDWVTNQR DFTDVDPQEI ELIRSLRNSD VPVYFGKIKT 840
  841 TIIVFGFFKV DKYKRIIDAI ETHNPPVIIN SKGLWIDMPK YALEICQKKQ LNVAGAIHGA 900
  901 QHAIMGMLPR FIVAGVDEIQ TECKAPEKEF AERQTKRKRP ARLIFYDSKG GKYGSGLCVK 960
  961 AFEHIDDIIE SSLRRIEECP CSDGCPDCVA ASFCKENSLV LSKPGAQVVL HCILGHSEDS1020
 1021 FIDLIKDGPE PNMPEIKVET VIPVSEHVNF SDDFKIIDVR RATKDDTHTN EIIKKEI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) DRS1 ERB1 HAA1 HRQ1 MKT1 STE20 UBP1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data HRQ1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..255] MSA 27.684997 View MSA. No confident structure predictions are available.
    2 View Details [256..732] PSI-BLAST 90.39794 Initiation factor 4a
    3 View Details [733..883] MSA 1.195988 View MSA. No confident structure predictions are available.
    4 View Details [884..1077] MSA 1.022972 View MSA. No confident structure predictions are available.
    5 View Details [831..1015] Pfam 36.136677 No description for PF09369.1 was found. No confident structure predictions are available.
    6 View Details [1016..1077] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  2.23442113662155 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.22122084731597 bayes_pls_golite062009
  • DNA binding
    		•  2.16885651648653 bayes_pls_golite062009
  • binding
    		•  1.98377446854662 bayes_pls_golite062009
  • transcription factor activity
    		•  1.44593900614628 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.289025912917599 bayes_pls_golite062009
  • transcription activator activity
    		•  0.119156260169142 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.0014623387970365 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle