YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: PLP1

General Information:
Name(s) found: PLP1 / YDR183W [SGD]
Description(s) found:
Found 31 descriptions.
SHOW ALL
  • Protein that interacts with CCT (chaperonin containing TCP-1) complex and has a role in actin and tubulin folding; has weak similarity to phosducins, which are G-protein regulators [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 230 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IPILink to PubMed article]
    Biological Process: positive regulation of transcription from RNA polymerase II promoter by pheromones [IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: GTPase inhibitor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDKLDRYYT NVLSNAEKDK HTTVDSDDKS SGEENLDELL NELDRELDED HEFLSAYRSE  60
   61 RLQQISDHLK QVKKNVEDDG YGRLQCIDNE ADAIQICTKT TMVVIHFELE TFGKCQYMNE 120
  121 KLENLAKRYL TTRFIKVNVQ TCPFLVNKLN IKVLPFVVGY KNGLEKVRYV GFSKLGNDPN 180
  181 GFDIRRLEQS LAHSGVIEDT FEIRKHSSVN TERFASTNHD RSESDSDLDI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data PLP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..230] PSI-BLAST 35.30103 Phosducin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein disulfide isomerase activity
    		•  1.68569917663071 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing S-S bonds
    		•  1.68569917663071 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting keto- and enol-groups
    		•  1.54950120532 bayes_pls_golite062009
  • protein binding
    		•  0.929222032081313 bayes_pls_golite062009
  • antioxidant activity
    		•  0.886564621488533 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.785931390209245 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • peroxidase activity
    		•  0.643723232606652 bayes_pls_golite062009
  • oxidoreductase activity, acting on peroxide as acceptor
    		•  0.643723232606652 bayes_pls_golite062009
  • disulfide oxidoreductase activity
    		•  0.435282747055884 bayes_pls_golite062009
  • binding
    		•  0.356664892576802 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle