YRC Public Data Repository - Protein Structure Prediction

Protein:	PLP1
Organism:	Saccharomyces cerevisiae
Length:	230 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PLP1.

Description	E-value	Query Range	Subject Range
PLP1 - Protein that interacts with CCT (chaperonin containing TCP-1) complex and has a role in actin and tu... gi\|151942167 - gi\|151942167\|gb\|EDN60523.1\| phosducin-like protein [Saccharomyces cerevisiae YJM789] PLP1_YEAST - Phosducin-like protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PLP1 PE=1 SV=1 gi\|190404860 - gi\|190404860\|gb\|EDV08127.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] gi\|207346621 - gi\|207346621\|gb\|EDZ73066.1\| YDR183Wp-like protein [Saccharomyces cerevisiae AWRI1631]	1.0E-43	[1..230]	[1..230]
PDCL3 - phosducin-like 3	1.0E-42	[3..229]	[11..239]
gi\|12835481 - gi\|12835481\|dbj\|BAB23267.1\| unnamed protein product [Mus musculus]	3.0E-42	[3..229]	[11..239]
gi\|10443855, gi\|... - gi\|9967826\|emb\|CAC06398.1\| phosducin-like protein [Bos taurus], gi\|27807471\|ref\|NP_777184.1\| phosduc...	9.0E-36	[6..230]	[8..217]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-35	[6..230]	[91..300]

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Predicted Domain #1

Region A:
Residues: [1-230]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDKLDRYYT NVLSNAEKDK HTTVDSDDKS SGEENLDELL NELDRELDED HEFLSAYRSE  60
   61 RLQQISDHLK QVKKNVEDDG YGRLQCIDNE ADAIQICTKT TMVVIHFELE TFGKCQYMNE 120
  121 KLENLAKRYL TTRFIKVNVQ TCPFLVNKLN IKVLPFVVGY KNGLEKVRYV GFSKLGNDPN 180
  181 GFDIRRLEQS LAHSGVIEDT FEIRKHSSVN TERFASTNHD RSESDSDLDI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.30103
Match:	1b9yC_
Description:	Phosducin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein disulfide isomerase activity	1.68569917663071	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds	1.68569917663071	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups	1.54950120532	bayes_pls_golite062009
protein binding	0.929222032081313	bayes_pls_golite062009
antioxidant activity	0.886564621488533	bayes_pls_golite062009
transcription regulator activity	0.785931390209245	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
peroxidase activity	0.643723232606652	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	0.643723232606652	bayes_pls_golite062009
disulfide oxidoreductase activity	0.435282747055884	bayes_pls_golite062009
binding	0.356664892576802	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: