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Protein Overview: GPR1

General Information:
Name(s) found: GPR1 / YDL035C [SGD]
Description(s) found:
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  • gi|6320170|ref|NP_010249.1| Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cA [NCBI NR]
  • gi|26394417|sp|Q12361.1|GPR1_YEAST RecName: Full=G protein-coupled receptor GPR1 [NCBI NR]
  • pir||S67568 probable membrane protein YDL035c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1431015|emb|CAA98593.1| GPR1 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1279681|emb|CAA96454.1| unknown [Saccharomyces cerevisiae] [NCBI NR]
  • G protein-coupled receptor GPR1 OS=Saccharomyces cerevisiae GN=GPR1 PE=1 SV=1 [Swiss-Prot]
  • GPR1 G-protein coupled receptor [mips]
  • Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis [SGD]
  • GPR1, Chr IV from 389168-392053, reverse complement [yeast_orfs2]
  • Chr IV from 389168-392053, reverse complement [yeastorf3.fasta]
  • Chr IV from 392053-389168, reverse complement [yeastorf5.fasta]
  • (Q12361) G protein-coupled receptor GPR1 [4932.FASTACCERV.txt]
  • GPR1 SGDID:S0002193, Chr IV from 392054-389169, reverse complement, Verified ORF [yeastflysequest.fasta]
  • Gpr1p [Saccharomyces cerevisiae]gi|1279681|emb|CAA96454.1| unknown [Saccharomyces cerevisiae]gi|1431015|emb|CAA98593.1| GPR1 [Saccharomyces cerevisiae]gi|2132416|pir||S67568 probable membrane protein YDL035c - yeast (Saccharomyces cerevisiae)gi|263944 [nrdb_11152004_Chlamydomonas]
  • GPR1 SGDID:S000002193, Chr IV from 392054-389169, reverse complement, Verified ORF, "Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritiona [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • GPR1 SGDID:S000002193, Chr IV from 392055-389170, reverse complement, Verified ORF, "Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritiona [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis; Gpr1p [Sacchar [nr-271106-contam.fasta]
  • unknown [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • GPR1 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • G protein-coupled receptor GPR1 [nr-271106-contam.fasta]
  • GPR1 SGDID:S000002193, Chr IV from 392055-389170, reverse complement, Verified ORF, "Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis" [yeast-bovrabprots.fasta]
  • GPR1 SGDID:S000002193, Chr IV from 392054-389169, reverse complement, Verified ORF, "Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis" [yeast-contam_custom.fasta]
  • [chemostatdb.fasta]
  • G protein-coupled receptor GPR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GPR1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • GPR1 SGDID:S000002193, Chr IV from 392057-389172, Genome Release 64-1-1, reverse complement, Verified ORF, "Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis" [yeast-030211-contam.fasta]
  • GPR1 SGDID:S000002193, Chr IV from 392057-389172, Genome Release 64-2-1, reverse complement, Verified ORF, "Plasma membrane G protein coupled receptor (GPCR); interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis" [20141208_orf_trans.fasta]
  • YDL035C SGDID:S000002193, Chr IV from 392057-389172, Genome Release 64-1-1, reverse complement, Verified ORF, "Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 961 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDALink to PubMed articleLink to PubMed article]
    Biological Process: G-protein coupled receptor protein signaling pathway [IMPLink to PubMed article][IPILink to PubMed article]
    pseudohyphal growth [IMPLink to PubMed article]
    replicative cell aging [IMPLink to PubMed article]
    Molecular Function: G-protein coupled receptor activity [IMPLink to PubMed article][IPILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MITEGFPPNL NALKGSSLLE KRVDSLRQLN TTTVNQLLGL PGMTSTFTAP QLLQLRIIAI  60
   61 TASAVSLIAG CLGMFFLSKM DKRRKVFRHD LIAFLIICDF LKAFILMIYP MIILINNSVY 120
  121 ATPAFFNTLG WFTAFAIEGA DMAIMIFAIH FAILIFKPNW KWRNKRSGNM EGGLYKKRSY 180
  181 IWPITALVPA ILASLAFINY NKLNDDSDTT IILDNNNYNF PDSPRQGGYK PWSAWCYLPP 240
  241 KPYWYKIVLS WGPRYFIIIF IFAVYLSIYI FITSESKRIK AQIGDFNHNV LEEEKEKKKL 300
  301 FGLGHWGKAK WYFRSYFKLP LLHLLRNLKN FFTISFIDPN EETDDSGSSN GTFNFGESSN 360
  361 EIPTLFRKTN TGSDENVSAS GGVRLLDYNS AKPLDMSKYA MSEQPDLERN NPFDCENDIT 420
  421 LNPSELVSKQ KEHKVTFSVE NEGLDTRKSS MLGHQTFSCQ NSLESPLAMY DNKNDNSDIT 480
  481 SNIKEKGGII NNNSNNDDDD NNNNNDNDND NNNSNNNNNN NNNNNNNNNN NNNNNNNNNN 540
  541 NNNNSNNIKN NVDNNNTNPA DNIPTLSNEA FTPSQQFSQE RVNNNADRCE NSSFTNVQQH 600
  601 FQAQTYKQMK KRRAQIQKNL RAIFIYPLSY IGIWLFPIIA DALQYNHEIK HGPTMWVTYI 660
  661 DTCVRPLSCL VDVIVYLFKE KPWNYSWAKT ESKYLIEKYI LKGELGEKEI LKFCHSNWGK 720
  721 RGWYYRGKWK KRKCWKYSTN PLKRILWFVE RFFKQLFELK LHFSFYDNCD DFEYWENYYS 780
  781 AKDSNDNKRT ESDETKTNSS DRSLPSNSLE LQAMLNNITA EEVEVPLFWR IIHHIPMLGG 840
  841 IDLDELNRLL KIRYNNDHFS LPGLKFALNQ NKSHDKHQDV STNSMVKSSF FSSNIVTNDD 900
  901 ENSIEEDKNL RYSDASASEN YLVKPTIPGT TPDPIIEAQN DNDSSDSSGI DLIAFLRNGP 960
  961 L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run IPL1 No Comments Cheeseman IM, et al. (2002)
    View Run NOP9 No Comments Hazbun TR, et al. (2003)
    View Run MIA40 No Comments Hazbun TR, et al. (2003)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..288] FFAS03 5.44 Rhodopsin
    2 View Details [289..680] PSI-BLAST 3.045757 Crystal structure of EBA-175 Region II (RII)
    3 View Details [681..880] deduced N/A No confident structure predictions are available.
    4 View Details [881..961] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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