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Protein Overview: RDS1

General Information:
Name(s) found: RDS1 / YCR106W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Zinc cluster transcription factor involved in conferring resistance to cycloheximide [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 832 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article]
    Biological Process: response to xenobiotic stimulus [IMPLink to PubMed article]
    Molecular Function: DNA binding [IPILink to PubMed article]
    transcription factor activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSITVKKPR LRLVCLQCKK IKRKCDKLRP ACSRCQQNSL QCEYEERTDL SANVAANDSD  60
   61 GFNSSHKLNF EQQPVLERTG LRYSLQVPEG VVNATLSIWN AEDMLVIVGL VTFLDYPFAA 120
  121 HSLAQHDQYI RALCASLYGM ALVDFSNYAN GIPCEDTSRS ILGPLSFIEK AIFRRIEHSK 180
  181 QFRVQSAALG LLYNAFSMEE ENFSTLLPSL IAEVEDVLMQ KKDCEILLRC FYQNIYPFYP 240
  241 FMDISLFESD LTSLLLQDDN NRWKISTEVK NVRKKIETLS LLTIVMAMAL MHSKLDANLL 300
  301 SMVKENASES ARKLSLLCHK LLCLLDVFRY PNENTFTCLL YFYVSEHLDP ESPDCVLSPT 360
  361 NLLTLHHLLN LSMTLGLQYE PSKYKRFKDP EVIRQRRILW LGVQSLLFQI SLAEGDAGKS 420
  421 NSEYMEAYLT DFEEYIEASS EYEKSSASES NVQMNDIVWN KYKFHVILSK LMSDCTSVIQ 480
  481 HPQLFHILGN IKRSEDFMAE NFPTSSIYQP LHEKEPNAIK VGKSTVLDVM DIQKTEIFLT 540
  541 NIVGSMCFLN IFDVLSLHFE KKCVMHWEEY EKNYHFLTLK SFNAYLKLAG LISDYLENKF 600
  601 QGNILESRGY IIDKQICFML VRIWMFQCRI LLRFSYKQES QKKLASSSIS TNDNEKEDEM 660
  661 IVILERLIKH IRNQMAHLVD LAKGKLQDSY FGAYQTVPMF RYVVYLIDVG GLVSVTNGFW 720
  721 DKISSDGEIP PKVQQAVRLK WGLDCNNSRR IKQKLISSQS LQSFNQVLLC QMEDAVLSSS 780
  781 FAIKANTAMS QNTAEEFFNI SEEEALNQLL ENNNFDAFWD LLGENLSDMP SL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CDC48 RDS1 1 Unpublished Fields Lab Data
    View Screen MDM1 RDS1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..100] PSI-BLAST 49.38764 Hap1 (Cyp1); HAP1
    2 View Details [101..514] MSA 1.131971 View MSA. No confident structure predictions are available.
    3 View Details [515..832] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  4.16002381293778 bayes_pls_golite062009
  • DNA binding
    		•  3.92936270801133 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.76909067702445 bayes_pls_golite062009
  • binding
    		•  2.91929847152301 bayes_pls_golite062009
  • transcription factor activity
    		•  2.76608547022152 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.80020012839068 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.69026374220371 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.54700248976411 bayes_pls_golite062009
  • transcription activator activity
    		•  0.778623988601299 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle