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Protein Overview: PER1

General Information:
Name(s) found: PER1 / YCR044C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Protein of the endoplasmic reticulum, required for GPI-phospholipase A2 activity that remodels the GPI anchor as a prerequisite for association of GPI-anchored proteins with lipid rafts; functionally complemented by human ortholog PERLD1 [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 357 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole membrane [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: GPI anchor biosynthetic process [IMPLink to PubMed article]
    cellular manganese ion homeostasis [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLAVVVTLL VHCFLVTCSP GDNLDEFIDC TYACEYNRRC PNSQINYIDP ETNMFHDIEF  60
   61 FDTPPLYSKL LFWDCISDCD YQCQHIITRW RIDEEEEIYQ FHGKWPFLRV LGTQEFFSTI 120
  121 FSIGNFIPHY KGFVKFSRII REEGDRRRKN SRSILIWNYL YVTVAGMLAW TASSVFHCRD 180
  181 LIITEKLDYF FAGLTVLTGF HAIFARMTSM FLYPKIAQAF TASVAAIFAL HILRLYVDWS 240
  241 YTYNMRFNIF FGVLQYILLI MLSCQNYHAL QKQKLMGEFK KTAYSSFKRQ IFKLCVIPIL 300
  301 LVIVTTMAMS LELFDFFSYE WQIDAHALWH LCTIWPSWVL YDFFLEDYAY WGNRQLY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PER1 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..98] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [99..357] MSA 1.008953 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle