Protein Overview: BUD5

General Information:
Name(s) found:	BUD5 / YCR038C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|45644958\|sp\|P25300.2\|BUD5_YEAST RecName: Full=Bud site selection protein 5 [NCBI NR] gi\|14588948\|emb\|CAA42305.2\| GDP/GTP exchange factor for Rsr1p/Bud1p [Saccharomyces cerevisiae] [NCBI NR] gi\|10383799\|ref\|NP_009967.2\| GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types; Bud5p [Saccharomyces cerevisiae] [NCBI NR] Bud site selection protein 5 OS=Saccharomyces cerevisiae GN=BUD5 PE=1 SV=2 [Swiss-Prot] BUD5 GDP/GTP exchange factor for Rsr1p/Bud1p [mips] GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types [SGD] BUD5, Chr III from 197613-199541, reverse complement [yeast_orfs2] Chr III from 197613-199541, reverse complement [yeastorf3.fasta] Chr III from 199541-197613, reverse complement [yeastorf5.fasta] >CAA42305 (CAA42305) GDP/GTP exchange factor for Rsr1p/Bud1p [4932.FASTACCERV.txt] BUD5 SGDID:S0000634, Chr III from 199544-197616, reverse complement, Verified ORF [yeastflysequest.fasta] Bud5p [Saccharomyces cerevisiae]gi\|14588948\|emb\|CAA42305.2\| GDP/GTP exchange factor for Rsr1p/Bud1p [Saccharomyces cerevisiae]gi\|45644958\|sp\|P25300\|BUD5_YEAST Bud site selection protein BUD5 [nrdb_11152004_Chlamydomonas] (P25300) Bud site selection protein BUD5 [cerv4932.FASTAC] BUD5 SGDID:S000000634, Chr III from 199544-197616, reverse complement, Verified ORF, "GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] BUD5 SGDID:S000000634, Chr III from 199545-197617, reverse complement, Verified ORF, "GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types" [yeast-contam.fasta] GDP/GTP exchange factor for Rsr1p/Bud1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Bud site selection protein BUD5 [nr-271106-contam.fasta] GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types; Bud5p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Bud site selection protein 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BUD5 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] BUD5 SGDID:S000000634, Chr III from 199549-197621, Genome Release 64-1-1, reverse complement, Verified ORF, "GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types" [yeast-030211-contam.fasta] BUD5 SGDID:S000000634, Chr III from 199549-197621, Genome Release 64-2-1, reverse complement, Verified ORF, "GTP/GDP exchange factor for Rsr1p (Bud1p); required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types" [20141208_orf_trans.fasta] YCR038C SGDID:S000000634, Chr III from 199549-197621, Genome Release 64-1-1, reverse complement, Verified ORF, "GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	642 amino acids
Gene Ontology:
Cellular Component:	incipient cellular bud site [IDA] cellular bud neck [IDA]
Biological Process:	axial cellular bud site selection [TAS ] cellular bud site selection [TAS] bipolar cellular bud site selection [TAS ] small GTPase mediated signal transduction [TAS] pseudohyphal growth [TAS]
Molecular Function:	guanyl-nucleotide exchange factor activity [TAS ] Ras guanyl-nucleotide exchange factor activity [TAS] signal transducer activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPKNKYVYI CVEYIYIYFA KIHKQSTLSS DTTKMFVLID NVLAYLLEQD DLFVTARFAI  60
   61 QGQIVSRRVN KIHISNITDV LLQQFISHTL PYNDNIVPKK ILDSMRTAVR QLLEATACVS 120
  121 RECPLVKRSQ DIKRARKRLL SDWYRLGADA NMDAVLLVVN SAWRFLAVWR PFVNSIQHAT 180
  181 QELYQNIAHY LLHGNVNIQR VTALIQLVMG QDDLLFSMDD VLQEVFRIQL YLNKMLPHNS 240
  241 HKWQKPSPFD SANLLLNFRD WTTDNALLQE LLLSYPTINK NKHKNHSVPR LIQIWVESYW 300
  301 QDSETTLKDI LNFWYSHLAE YYEYQELFAD IVQLFINKKR TRQLKIHYIG LTDKEIEENK 360
  361 PPLDYENLFL QYEIDKTNAN DELCGATDLS DLLFQWKQGE LLEVEAFALN VSPWSLAKTL 420
  421 TLLESSLYLD IETIEFTRHF KHNDTTIDSV FTLSNQLSSY VLETTLQQTH TISYWLQVAL 480
  481 SCLYLRNLNS LASIITSLQN HSIERLSLPI DVKSDHLFQR LKVVVHPNNN YNVYRRTIKH 540
  541 IFHSQLPCVP FTSLLIRDIT FIRDGNDTFT KDGNNVNMQK FNQITKIVAF AQYLQQKQYE 600
  601 DIHCSNTTAR SLLGAMIKVH TLYNDNKDRA YQVSIAKVPR LT

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		BUD5 IRC7 PHO11 PHO5
View Details	Qiu et al. (2008)		BUD5 CDC24 GIC1 LRG1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	BUD5	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..150]	deduced	N/A	No confident structure predictions are available.
2	View Details	[151..359] [560..586]	PSI-BLAST	112.0	Son of sevenless protein homolog 1 (sos-1)
3	View Details	[360..559] [587..642]	PSI-BLAST	112.0	Son of sevenless protein homolog 1 (sos-1)

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.90

Protein Overview: BUD5

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: