YRC Public Data Repository - Protein Structure Prediction

Protein:	BUD5
Organism:	Saccharomyces cerevisiae
Length:	642 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BUD5.

Description	E-value	Query Range	Subject Range
BUD5_YEAST - Bud site selection protein 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BUD5 PE=1 S... BUD5 - GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; muta... gi\|151943859 - gi\|151943859\|gb\|EDN62159.1\| GTP/GDP exchange factor for Rsr1 protein [Saccharomyces cerevisiae YJM78...	0.0	[1..642]	[1..642]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[105..642]	[1..538]
GNDS_RAT - Ral guanine nucleotide dissociation stimulator OS=Rattus norvegicus GN=Ralgds PE=1 SV=1	0.0	[174..639]	[62..628]
gi\|119608444, gi... - gi\|18676576\|dbj\|BAB84940.1\| FLJ00185 protein [Homo sapiens], gi\|119608444\|gb\|EAW88038.1\| ral guanine...	0.0	[174..639]	[62..635]
GNDS_MOUSE - Ral guanine nucleotide dissociation stimulator OS=Mus musculus GN=Ralgds PE=1 SV=1	2.0E-99	[174..639]	[7..585]

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Predicted Domain #1

Region A:
Residues: [1-150]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPKNKYVYI CVEYIYIYFA KIHKQSTLSS DTTKMFVLID NVLAYLLEQD DLFVTARFAI  60
   61 QGQIVSRRVN KIHISNITDV LLQQFISHTL PYNDNIVPKK ILDSMRTAVR QLLEATACVS 120
  121 RECPLVKRSQ DIKRARKRLL SDWYRLGADA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [151-359]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMDAVLLVVN SAWRFLAVWR PFVNSIQHAT QELYQNIAHY LLHGNVNIQR VTALIQLVMG  60
   61 QDDLLFSMDD VLQEVFRIQL YLNKMLPHNS HKWQKPSPFD SANLLLNFRD WTTDNALLQE 120
  121 LLLSYPTINK NKHKNHSVPR LIQIWVESYW QDSETTLKDI LNFWYSHLAE YYEYQELFAD 180
  181 IVQLFINKKR TRQLKIHYIG LTDKEIEEN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [560-586]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFIRDGNDTF TKDGNNVNMQ KFNQITK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	112.0
Match:	1bkdS_
Description:	Son of sevenless protein homolog 1 (sos-1)
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [360-559]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPPLDYENLF LQYEIDKTNA NDELCGATDL SDLLFQWKQG ELLEVEAFAL NVSPWSLAKT  60
   61 LTLLESSLYL DIETIEFTRH FKHNDTTIDS VFTLSNQLSS YVLETTLQQT HTISYWLQVA 120
  121 LSCLYLRNLN SLASIITSLQ NHSIERLSLP IDVKSDHLFQ RLKVVVHPNN NYNVYRRTIK 180
  181 HIFHSQLPCV PFTSLLIRDI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [587-642]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVAFAQYLQQ KQYEDIHCSN TTARSLLGAM IKVHTLYNDN KDRAYQVSIA KVPRLT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	112.0
Match:	1bkdS_
Description:	Son of sevenless protein homolog 1 (sos-1)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits