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Protein Overview: BUD5

General Information:
Name(s) found: BUD5 / YCR038C [SGD]
Description(s) found:
Found 23 descriptions.
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  • GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 642 amino acids

    Gene Ontology:
    Cellular Component: incipient cellular bud site [IDALink to PubMed article]
    cellular bud neck [IDALink to PubMed article]
    Biological Process: axial cellular bud site selection [TASLink to PubMed articleLink to PubMed articleLink to PubMed article]
    cellular bud site selection [TASLink to PubMed article]
    bipolar cellular bud site selection [TASLink to PubMed articleLink to PubMed articleLink to PubMed article]
    small GTPase mediated signal transduction [TASLink to PubMed article]
    pseudohyphal growth [TASLink to PubMed article]
    Molecular Function: guanyl-nucleotide exchange factor activity [TASLink to PubMed articleLink to PubMed article]
    Ras guanyl-nucleotide exchange factor activity [TASLink to PubMed article]
    signal transducer activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPKNKYVYI CVEYIYIYFA KIHKQSTLSS DTTKMFVLID NVLAYLLEQD DLFVTARFAI  60
   61 QGQIVSRRVN KIHISNITDV LLQQFISHTL PYNDNIVPKK ILDSMRTAVR QLLEATACVS 120
  121 RECPLVKRSQ DIKRARKRLL SDWYRLGADA NMDAVLLVVN SAWRFLAVWR PFVNSIQHAT 180
  181 QELYQNIAHY LLHGNVNIQR VTALIQLVMG QDDLLFSMDD VLQEVFRIQL YLNKMLPHNS 240
  241 HKWQKPSPFD SANLLLNFRD WTTDNALLQE LLLSYPTINK NKHKNHSVPR LIQIWVESYW 300
  301 QDSETTLKDI LNFWYSHLAE YYEYQELFAD IVQLFINKKR TRQLKIHYIG LTDKEIEENK 360
  361 PPLDYENLFL QYEIDKTNAN DELCGATDLS DLLFQWKQGE LLEVEAFALN VSPWSLAKTL 420
  421 TLLESSLYLD IETIEFTRHF KHNDTTIDSV FTLSNQLSSY VLETTLQQTH TISYWLQVAL 480
  481 SCLYLRNLNS LASIITSLQN HSIERLSLPI DVKSDHLFQR LKVVVHPNNN YNVYRRTIKH 540
  541 IFHSQLPCVP FTSLLIRDIT FIRDGNDTFT KDGNNVNMQK FNQITKIVAF AQYLQQKQYE 600
  601 DIHCSNTTAR SLLGAMIKVH TLYNDNKDRA YQVSIAKVPR LT

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) BUD5 IRC7 PHO11 PHO5
    View Details Qiu et al. (2008) BUD5 CDC24 GIC1 LRG1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data BUD5 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..150] deduced N/A No confident structure predictions are available.
    2 View Details [151..359]
    [560..586]    		 PSI-BLAST 112.0 Son of sevenless protein homolog 1 (sos-1)
    3 View Details [360..559]
    [587..642]    		 PSI-BLAST 112.0 Son of sevenless protein homolog 1 (sos-1)


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle