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Protein Overview: YPC1

General Information:
Name(s) found: YPC1 / YBR183W [SGD]
Description(s) found:
Found 32 descriptions.
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  • Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity, catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 316 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: ceramide metabolic process [IMPLink to PubMed article]
    Molecular Function: ceramidase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIFRWNYPE SSVPGVWGET TSTIDWCEEN YVVSPYIAEW SNTLTNSVFI LSAIYTTYSA  60
   61 YKNKLEKRFL LIGFGYGLVG VGSWLFHMTL KYRFQLLDEL PMIYAMCIPT WSLVCEAKEA 120
  121 LLNGDNHKKV PLFEQIFIGV IIGLAVTTAS ILYVIYKNVD IHQILFGVQI VVVAATAGSL 180
  181 TYRYVHDPLA KRNLKASMAL GAILFLSGYI SWLLDIHYCS FWVHVRRSIL ALPLGVLLEP 240
  241 HGWWHILTGM GIYFYIVSLE HLRVITLNVS CNYQFIWRWK VFPELIWKGR KPSTRYSLEL 300
  301 FGPYVEDQSI EVKKEK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) YDC1 YPC1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..186] MSA 1.014963 View MSA. No confident structure predictions are available.
    2 View Details [187..316] MSA 1.014985 View MSA. Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle