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Protein Overview: GRX7

General Information:
Name(s) found: GRX7 / YBR014C [SGD]
Description(s) found:
Found 34 descriptions.
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  • Cis-golgi localized monothiol glutaredoxin; more similar in activity to dithiol than other monothiol glutaredoxins; involved in the oxidative stress response; does not bind metal ions; functional overlap with GRX6 [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 203 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDALink to PubMed article]
    fungal-type vacuole [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIVINKRNV RVLVITNLLL IVVFFVLRNS NASVNESITT HHPDSLVTFD NSGNAPGTHQ  60
   61 SVHDTVNTQD KEAEEVDKNS GDAEFDAAAE YNKIMEQSPM IVFSKTGCPY SKKLKALLTN 120
  121 SYTFSPSYYV VELDRHEHTK ELQDQIEKVT GRRTVPNVII GGTSRGGYTE IAELHKNDEL 180
  181 LDSFKKWSDG AFTVKANSQS ESA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) GET1 GET2 GET3 GRX7 POR1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run VAM3 Sample: HX14 - mixture in detergent (control). Hao Xu, et al. (2010)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GRX7 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..81] deduced N/A No confident structure predictions are available.
    2 View Details [82..203] PSI-BLAST 139.0 Glutaredoxin (Grx, thioltransferase)


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle