YRC Public Data Repository - Protein Structure Prediction

Protein:	GRX7
Organism:	Saccharomyces cerevisiae
Length:	203 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GRX7.

Description	E-value	Query Range	Subject Range
GLRX7_YEAST - Monothiol glutaredoxin-7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GRX7 PE=1 SV=1 GRX7 - Cis-golgi localized monothiol glutaredoxin; more similar in activity to dithiol than other monothiol...	6.0E-56	[1..203]	[1..203]
gi\|2724050, gi\|2... - gi\|2724056\|gb\|AAB92658.1\| glutaredoxin type I [Fritillaria agrestis], gi\|2724054\|gb\|AAB92657.1\| glut...	4.0E-32	[87..192]	[2..104]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-31	[87..195]	[2..107]
gi\|116310771, gi... - gi\|125548975\|gb\|EAY94797.1\| hypothetical protein OsI_16580 [Oryza sativa Indica Group], gi\|116310771... GRXC6_ORYSA, GLR... - Glutaredoxin-C6 (Glutaredoxin-C2 homolog 1) - Oryza sativa (Rice), (P55142) Glutaredoxin GRXC6_ORYSJ - Glutaredoxin-C6 OS=Oryza sativa subsp. japonica GN=GRXC6 PE=1 SV=2	4.0E-31	[87..195]	[2..107]
GRXC2_ARATH - Glutaredoxin-C2 OS=Arabidopsis thaliana GN=GRXC2 PE=2 SV=1	8.0E-31	[87..191]	[2..103]
GLRX2 - glutaredoxin 2	8.0E-31	[48..196]	[16..162]
gi\|65811 - pir\|\|GDPG glutaredoxin - pig GLRX1_PIG - Glutaredoxin-1 OS=Sus scrofa GN=GLRX PE=1 SV=2	2.0E-30	[87..191]	[2..106]

Back

Predicted Domain #1

Region A:
Residues: [1-81]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIVINKRNV RVLVITNLLL IVVFFVLRNS NASVNESITT HHPDSLVTFD NSGNAPGTHQ  60
   61 SVHDTVNTQD KEAEEVDKNS G

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [82-203]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAEFDAAAEY NKIMEQSPMI VFSKTGCPYS KKLKALLTNS YTFSPSYYVV ELDRHEHTKE  60
   61 LQDQIEKVTG RRTVPNVIIG GTSRGGYTEI AELHKNDELL DSFKKWSDGA FTVKANSQSE 120
  121 SA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	139.0
Match:	1b4qA_
Description:	Glutaredoxin (Grx, thioltransferase)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits