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Protein Overview: SRO77

General Information:
Name(s) found: SRO77 / YBL106C [SGD]
Description(s) found:
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  • gi|6319362|ref|NP_009444.1| Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro7p and Drosophila lethal giant larvae tumor suppressor; interacts with SNARE pr [NCBI NR]
  • pir||S45389 probable membrane protein YBL106c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|586462|sp|P38163.1|SNI2_YEAST RecName: Full=Protein SNI2; AltName: Full=Suppressor of RHO3 protein 77 [NCBI NR]
  • gi|536180|emb|CAA84933.1| SNI2 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|498989|emb|CAA55989.1| E-1010 protein [Saccharomyces cerevisiae] [NCBI NR]
  • Protein SNI2 OS=Saccharomyces cerevisiae GN=SNI2 PE=1 SV=1 [Swiss-Prot]
  • SRO77 Polarized exocytosis by regulating SNARE function [mips]
  • Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro7p and Drosophila lethal giant larvae tumor suppressor; interacts with SNARE protein Sec9p [SGD]
  • SRO77, Chr II from 10847-13879, reverse complement [yeast_orfs2]
  • Chr II from 10847-13879, reverse complement [yeastorf3.fasta]
  • Chr II from 13879-10847, reverse complement [yeastorf5.fasta]
  • (P38163) SNI2 protein (SRO77 protein) [4932.FASTACCERV.txt]
  • SRO77 SGDID:S0000202, Chr II from 13879-10847, reverse complement, Verified ORF [yeastflysequest.fasta]
  • Sro77p [Saccharomyces cerevisiae]gi|498989|emb|CAA55989.1| E-1010 protein [Saccharomyces cerevisiae]gi|536180|emb|CAA84933.1| SNI2 [Saccharomyces cerevisiae]gi|586462|sp|P38163|SNI2_YEAST SNI2 protein (SRO77 protein)gi|626202|pir||S45389 probable memb [nrdb_11152004_Chlamydomonas]
  • SRO77 SGDID:S000000202, Chr II from 13879-10847, reverse complement, Verified ORF, "Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro7p and Drosophila letha [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro7p and Drosophila lethal giant larvae tumor suppressor; interacts with SNARE protein Sec9p; Sro77p [Sacchar [nr-271106-contam.fasta]
  • E-1010 protein [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Protein SNI2 (Suppressor of RHO3 protein 77) [nr-271106-contam.fasta]
  • SNI2 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • SRO77 SGDID:S000000202, Chr II from 13879-10847, reverse complement, Verified ORF, "Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro7p and Drosophila lethal giant larvae tumor suppressor; interacts with SNARE protein Sec9p" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 1010 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IPILink to PubMed article][ISSLink to PubMed article]
    Biological Process: Golgi to plasma membrane transport [IGILink to PubMed article][IPILink to PubMed article]
    exocytosis [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKKSRHLKN VSNAIKSARV HDVSNGINSK FFDTKKICTY GINGRITVTT FDYTQSLLAV  60
   61 ATTAGEIHVY GQKQIEVVFT LKNRPQIKHM RFIKGIYLIA VDEKSNIIVL SVHSKQILTT 120
  121 VFCPNSITCF ETDPPLDWML IGLESGSILI YDVDRNQMSK LKIENFQKSV FLPKERLSPV 180
  181 ISIQWNPRDI GTILISYEHI TVIYSFIDYK VKQHFFYQLE PYAPGGDLST NIEKKRTPKV 240
  241 IQSLYHPNSL HILTVHEDNA LVFWDVNSGK LIHARSIFET HVNFPNPALK DCSFTETPAI 300
  301 FKVSWLCQRN PEYTSLLIAT KATENPCLPQ EITMIDLGGT PMYSVTSFDA MSKYYAKPVQ 360
  361 QKLFSLIGKA PLINFLPLPK ASPYFGGCHD TNLILLLLED GELETLIYPA GSFSSKASIF 420
  421 PRSLAWVRPT VTTCIAQSVQ KNLWLGMMTI AQSESFLKGG IPATRNIRRH ETRSALLTGH 480
  481 SNGSVRIWDA SHSEVTDNAV FEVNTAKVLN RATNLAIKNI SFASETLELA VSSEVGDVIL 540
  541 FKFETNKFYG QLPKSDALQL KFSRFSLDDS KTILVDVSDR GPTNVKQGFI PSTVIHAKKG 600
  601 AVSAIMNSNI GFVAVGFIEG TLIILDRRGP AIIFNENIRV ISKAGSSYVS TVHFCVMEYG 660
  661 DDGFSSILML CGTDIGELMT FKILPATNGR FEVKFTDATK TNNQGKILGI NSFAKDTGYS 720
  721 CSATISKMQG LSKGIAIPGF VTISGANDIR LVSPGKSKDT HALFKYPIAT SGLSFIPIID 780
  781 GKGERKLSTI MIVLLINGDI KVLTVPELKE VKNLRCPVPL SAQYVENSSI LENVDIVIRT 840
  841 GKFQASLISV LNESATGSNH TADISQHTPI DTLYNPDLKI GYRPQVNSLQ WARGTIYCTP 900
  901 YQLDELLGGI ERPESKYEES AIARGCISSS SSNAARKLPP GTKDHRYARP VRSSGRSNGY 960
  961 GVLKSVSRAI ETRLDTVETT INDYATTMGQ TMNDAMEETG RDMMKSAVGF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ACF2 DTR1 LSB1 SBA1 SRO77 URA8 YGL140C YOR262W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SRO77 ENT2 2 Drees BL, et al. (2001)
    View Screen SRO77 APP1 2 Drees BL, et al. (2001)
    View Screen SRO77 MCA1 2 Drees BL, et al. (2001)
    View Screen SRO77 NIP100 2 Drees BL, et al. (2001)
    View Screen SRO77 KIN3 2 Drees BL, et al. (2001)
    View Screen SRO77 NFS1 2 Unpublished Fields Lab Data
    View Screen SRO77 YIP1 2 Drees BL, et al. (2001)
    View Screen SRO77 SFB3 2 Unpublished Fields Lab Data
    View Screen SRO77 BCY1 2 Drees BL, et al. (2001)
    View Screen SRO77 GMH1 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..301] PSI-BLAST 61.0 beta1-subunit of the signal-transducing G protein heterotrimer
    2 View Details [302..471] PSI-BLAST 2.39794 TolB, C-terminal domain; TolB, N-terminal domain
    3 View Details [472..716] MSA 5.543996 View MSA. No confident structure predictions are available.
    4 View Details [717..1010] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle