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Protein Overview: SBA1

General Information:
Name(s) found: SBA1 / YKL117W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Co-chaperone that binds to and regulates Hsp90 family chaperones; important for pp60v-src activity in yeast; homologous to the mammalian p23 proteins and like p23 can regulate telomerase activity [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 216 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: protein folding [IMPLink to PubMed article][IPILink to PubMed article][ISSLink to PubMed article]
    Molecular Function: chaperone binding [IMPLink to PubMed article][IPILink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDKVINPQV AWAQRSSTTD PERNYVLITV SIADCDAPEL TIKPSYIELK AQSKPHVGDE  60
   61 NVHHYQLHID LYKEIIPEKT MHKVANGQHY FLKLYKKDLE SEYWPRLTKE KVKYPYIKTD 120
  121 FDKWVDEDEQ DEVEAEGNDA AQGMDFSQMM GGAGGAGGAG GMDFSQMMGG AGGAGSPDMA 180
  181 QLQQLLAQSG GNLDMGDFKE NDEEDEEEEI EPEVKA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ACF2 DTR1 LSB1 SBA1 SRO77 URA8 YGL140C YOR262W

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SBA1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..216] PSI-BLAST 104.144602 Co-chaperone p23
    2 View Details [132..216] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle