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Protein Overview: Ih-PC, FBpp03009...

General Information:
Name(s) found: FBpp0300993 [FlyBase]
FBpp0300992 [FlyBase]
FBpp0300991 [FlyBase]
Ih-PC / FBpp0099778 [FlyBase]
Description(s) found:
Found 36 descriptions.
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  • type=protein; loc=2R:join(10178775..10178777,10178939..10179177,10179257..10179420,10179551..10179687,10179749..10179886,10184206..10184355,10184421..10184497,10184644..10184955,10185099..10185193,10185252..10185340,10185402..10185718,10185880..10186015); ID=FBpp0300993; name=Ih-PL; parent=FBgn0263397,FBtr0308836; dbxref=FlyBase:FBpp0300993,FlyBase_Annotation_IDs:CG8585-PL,REFSEQ:NP_001246320,GB_protein:AFH08074; MD5=1caf4e83decf100e72850b826c2189c4; length=618; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=2R:join(10178775..10178777,10178939..10179177,10179257..10179420,10179551..10179687,10179749..10179886,10184206..10184355,10184421..10184497,10184644..10184955,10185099..10185193,10185252..10185340,10185402..10185718,10185880..10186015); ID=FBpp0300992; name=Ih-PK; parent=FBgn0263397,FBtr0308835; dbxref=FlyBase:FBpp0300992,FlyBase_Annotation_IDs:CG8585-PK,REFSEQ:NP_001246318,GB_protein:AFH08072; MD5=1caf4e83decf100e72850b826c2189c4; length=618; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=2R:join(10178775..10178777,10178939..10179177,10179257..10179420,10179551..10179687,10179749..10179886,10184206..10184355,10184421..10184497,10184644..10184955,10185099..10185193,10185252..10185340,10185402..10185718,10185880..10186015); ID=FBpp0300991; name=Ih-PJ; parent=FBgn0263397,FBtr0308834; dbxref=FlyBase:FBpp0300991,FlyBase_Annotation_IDs:CG8585-PJ,REFSEQ:NP_001246319,GB_protein:AFH08073; MD5=1caf4e83decf100e72850b826c2189c4; length=618; release=r5.56; species=Dmel; [FlyBase]
  • The gene I<down>h</down> channel is referred to in FlyBase by the symbol Dmel\Ih (CG8585, FBgn0028428). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10166938..10186413. It has the cytological map location 50E6-50F1. Based on sequence similarity, it is predicted to have molecular function</span>: intracellular cyclic nucleotide activated cation channel activity; voltage-gated ion channel activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport; potassium ion transport. 5 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 618 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    plasma membrane [ISS]
    Biological Process: potassium ion transport [IEA]
    transmembrane transport [IEA]
    Molecular Function: voltage-gated potassium channel activity [IEA]
    voltage-gated ion channel activity [ISS][NAS]
    intracellular cyclic nucleotide activated cation channel activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVHFDDVSLY GTPKEEPMPN IPIVSEKVSA NFLKSQLQSW FQPTDNRLAM KLFGSRKALV  60
   61 KERIRQKTSG HWVIHPCSSF RFYWDLCMLL LLVANLIILP VAISFFNDDL STRWIAFNCL 120
  121 SDTIFLIDIV VNFRTGIMQQ DNAEQVILDP KLIAKHYLRT WFFLDLISSI PLDYIFLIFN 180
  181 QDFSDSFQIL HAGRALRILR LAKLLSLVRL LRLSRLVRYV SQWEEVYFLN MASVFMRIFN 240
  241 LICMMLLIGH WSGCLQFLVP MLQGFPSNSW VSINELQESY WLEQYSWALF KAMSHMLCIG 300
  301 YGRFPPQSLT DMWLTMLSMI SGATCYALFL GHATNLIQSL DSSRRQYREK VKQVEEYMAY 360
  361 RKLPRDMRQR ITEYFEHRYQ GKFFDEELIL GELSEKLRED VINYNCRSLV ASVPFFANAD 420
  421 SNFVSDVVTK LKYEVFQPGD IIIKEGTIGT KMYFIQEGVV DIVMANGEVA TSLSDGSYFG 480
  481 EICLLTNARR VASVRAETYC NLFSLSVDHF NCVLDQYPLM RKTMETVAAE RLNKIGKNPN 540
  541 IMHQKDEQLS NPESNTITAV VNALAAEADD CKDDDMDLKE NLLHGSESSI AEPVQTIREG 600
  601 LPRPRSGEFR ALFEGNTP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..362] PSI-BLAST 31.522879 Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
    2 View Details [363..418] PSI-BLAST 20.0 HCN2J 443-645 in the presence of cGMP
    3 View Details [419..618] PSI-BLAST 16.39794 No description for 2pqqA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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