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Protein Overview: TBX5_RAT

General Information:
Name(s) found: TBX5_RAT [Swiss-Prot]
Description(s) found:
Found 9 descriptions.
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  • T-box transcription factor TBX5 OS=Rattus norvegicus GN=Tbx5 PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 517 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][ISS]
    cytoplasm [UNKNOWN][ISS]
    cellular_component [ND]
    Biological Process: negative regulation of cardiac muscle cell proliferation [UNKNOWN][ISS]
    biological_process [ND]
    negative regulation of cell proliferation [UNKNOWN][ISS]
    cell-cell signaling [UNKNOWN][ISS]
    pattern specification process [UNKNOWN][IEA]
    positive regulation of transcription [UNKNOWN][ISS]
    bundle of His development [UNKNOWN][IEA]
    regulation of transcription [UNKNOWN]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    pericardium development [UNKNOWN][ISS]
    heart development [UNKNOWN][ISS]
    embryonic limb morphogenesis [UNKNOWN][ISS]
    positive regulation of cardioblast differentiation [UNKNOWN][ISS]
    morphogenesis of an epithelium [UNKNOWN][IEA]
    induction of apoptosis [UNKNOWN][ISS]
    positive regulation of transcription, DNA-dependent [UNKNOWN][ISS]
    positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA]
    forelimb morphogenesis [UNKNOWN]
    embryonic forelimb morphogenesis [UNKNOWN]
    negative regulation of cell migration [UNKNOWN][ISS]
    lung development [UNKNOWN][IEA]
    embryonic arm morphogenesis [UNKNOWN][ISS]
    Molecular Function: DNA binding [UNKNOWN][ISS]
    transcription factor activity [UNKNOWN][ISS]
    protein binding [UNKNOWN]
    RNA polymerase II transcription factor activity [UNKNOWN][ISS]
    sequence-specific DNA binding [UNKNOWN][ISS]
    transcription factor binding [UNKNOWN][IEA]
    transcription activator activity [UNKNOWN][IEA]
    molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADADEGFGL ARTPLEPDSK DRSCDSKPES ALGAPSKSPS SPQAAFTQQG MEGIKVFLHE  60
   61 RELWLKFHEV GTEMIITKAG RQMFPSYKVK VTGLNPKTKY ILLMDIVPAD DHRYKFADNK 120
  121 WSVTGKAEPA MPGRLYVHPD SPATGAHWMR QLVSFQKLKL TNNHLDPFGH IILNSMHKYQ 180
  181 PRLHIVKADE NNGFGSKNTA FCTHVFPETA FIAVTSYQNH KITQLKIENN PFAKGFRGSD 240
  241 DLELHRMSRM RSKEYPVVPR STVRHKVANH SPFSSETRAL STSSNLGSQY QCENGVSGPS 300
  301 QDLLPPPNPY PLAQEHSQIY HCTKRKDEEC SSTEHPYKKP YMETSPSEED TFYRSGYPQQ 360
  361 QGLSTSYRTE SAQRQACMYA SSAPPSEPVP SLEDISCNTW PSMPSYSSCT VTTVQPMDRL 420
  421 PYQHFSAHFT SGPLVPRLAG MANHGSPQLG EGMFQHQTSV THQPVVRQCG PQTGLQSPGS 480
  481 LQPPEFLYTH GVPRTLSPHQ YHSVHGVGMV PEWSENS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle