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Protein Overview: JIP5

General Information:
Name(s) found: JIP5 / YPR169W [SGD]
Description(s) found:
Found 16 descriptions.
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  • Essential protein required for biogenesis of the large ribosomal subunit; interacts with proteins involved in RNA processing, ribosome biogenesis, ubiquitination and demethylation; similar to WDR55, a human WD repeat protein [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 492 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    nucleolus [IDALink to PubMed articleLink to PubMed article]
    Biological Process: protein monoubiquitination [IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKSKKKTDV VDSTNLPILE LLSLKAPIFQ SLLHPELPII ITGFGTGHIV CHRYDPAKLQ  60
   61 SHLDRRRRID TATTGKDAKK GVCPWIRLDI DLETGDLKFV DIEEQQQQKQ TGKDEDLGVK 120
  121 TLWKTKRHKG SVRAMCFDSK GDNIFSVGSD NVLKKANTMT GKVVKKVNLS SLFNSEEKKN 180
  181 DKFTKLCASQ THPFILIGDE SGNIHVINSE NLALSNSIRS IHFGDSINDI FHFDKRSAYK 240
  241 FISLGQTTLA YFDVRDKDAK PNVAGNEDGK ILISDDQEDE VLCGCFVDPE VADTLLCGMG 300
  301 EGIVTVWKPN KNDLEDQMSR IKISKDESID CIVPTLQDDN CVWCGCSNGN IYKVNAKLGK 360
  361 VVEIRNHSEL DEVSFVDLDF EYRVVSGGLE NIKIWELSSD DVEENASVES DSDEPLSHSD 420
  421 EDLSDDTSSD DETTLVGLSK EELLDELDKD LKEDHQEEKE SNSKSVKKRK IMKENNKKKD 480
  481 LYEHGIKKFD DL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) JIP5 LUG1 NOP53 RPL5
    View Details Hazbun TR, et al. (2003) BRE1 JIP5
    View Details Krogan NJ, et al. (2006) JIP5 PUF6
    View Details Qiu et al. (2008) GAR1 JIP5 MAK5 UTP13 UTP4 UTP8 UTP9

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data JIP5 and NOP56 Huh WK, et al. (2003)
    View Data JIP5 Huh WK, et al. (2003)

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle