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Protein Overview: gi|4469395

General Information:
Name(s) found: gi|4469395 [NCBI NR]
Description(s) found:
Found 3 descriptions.
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  • gi|4469395|gb|AAD21242.1| myosin A [Plasmodium falciparum] [NCBI NR]
    • Organism: Plasmodium falciparum
    Length: 818 amino acids

    Gene Ontology:
    Cellular Component: pellicle [IDALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: NONE FOUND
    Molecular Function: actin binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVTNEEIKT ASKIVRRVSN VEAFDKSGSV FKGYQIWTDI SPTIENDPNI MFVKCVVQQG  60
   61 SKKEKLTVVQ IDPPGTGTPY DIDPTHAWNC NSQVDPMSFG DIGLLNHTNI PCVLDFLKHR 120
  121 YLKNQIYTTA VPLIVAINPY KDLGNTTNEW IRRYRDTADH TKLPPHVFTC AREALSNLHG 180
  181 VNKSQTIIVS GESGAGKTEA TKQIMRYFAS SKSGNMDLRI QTAIMAANPV LEAFGNAKTI 240
  241 RNNNSSRFGR FMQLVISHEG GIRYGSVVAF LLEKSRIITQ DDNERSYHIF YQFLKGANST 300
  301 MKSKFGLKGV TEYKLLNPNS TEVSGVDDVK DFEEVIESLK NMELSESDIE VIFSIVAGIL 360
  361 TLGNVRLIEK QEAGLSDAAA IMDEDMGVFN KACELMYLDP ELIKREILIK VTVAGGTKIE 420
  421 GRWNKNDAEV LKSSLCKAMY EKLFLWIIRH LNSRIEPEGG FKTFMGMLDI FGFEVFKNNS 480
  481 LEQLFINITN EMLQKNFVDI VFERESKLYK DEGISTAELK YTSNKEVINV LCEKGKSVLS 540
  541 YLEDQCLAPG GTDEKFVSSC ATNLKENNKF TPAKVASNKN FIIQHTIGPI QYCAESFLLK 600
  601 NKDVLRGDLV EVIKDSPNPI VQQLFEGQVI EKGKIAKGSL IGSQFLNQLT SLMNLINSTE 660
  661 PHFIRCIKPN ENKKPLEWCE PKILIQLHAL SILEALVLRQ LGYSYRRTFE EFLYQYKFVD 720
  721 IAAAEDSSVE NQNKCVNILK LSGLSESMYK IGKSMVFLKQ EGAKILTKIQ REKLVEWENC 780
  781 VSVIEAAILK HKYKQKVNKN IPSLLRVQAH IRKKMVAQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..89] MSA 1.192994 View MSA. No confident structure predictions are available.
    2 View Details [90..818] PSI-BLAST 1000.0 Myosin S1, motor domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • actin-dependent ATPase activity
    		•  5.83616693706338 bayes_pls_golite062009
  • microfilament motor activity
    		•  5.82833334737708 bayes_pls_golite062009
  • microtubule motor activity
    		•  4.51968578934603 bayes_pls_golite062009
  • motor activity
    		•  4.04927796049806 bayes_pls_golite062009
  • actin binding
    		•  3.33639699088484 bayes_pls_golite062009
  • transporter activity
    		•  3.10463051760206 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.95886887664984 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • tubulin binding
    		•  2.67743463093593 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  2.61775212528604 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  2.61467977505707 bayes_pls_golite062009
  • microtubule binding
    		•  2.59155206524122 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  2.57552435627908 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  2.57107347424517 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  2.57054427875021 bayes_pls_golite062009
  • hydrolase activity
    		•  2.55157966585974 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.50494515048649 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.43862163407966 bayes_pls_golite062009
  • ADP binding
    		•  2.42564874799906 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.4101693596493 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • actin filament binding
    		•  2.24723363507804 bayes_pls_golite062009
  • myosin light chain binding
    		•  2.23966366728473 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.91091452720653 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.56325751172863 bayes_pls_golite062009
  • signal recognition particle binding
    		•  1.51332809264918 bayes_pls_golite062009
  • plus-end-directed microtubule motor activity
    		•  1.38366133153678 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.977237423302079 bayes_pls_golite062009
  • structural constituent of muscle
    		•  0.960508657568442 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • GTPase activity
    		•  0.83849854735032 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.775560967092349 bayes_pls_golite062009
  • beta-tubulin binding
    		•  0.654735466720932 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.640772201693186 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.63468044350616 bayes_pls_golite062009
  • GTP binding
    		•  0.621689261700018 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.557919489256916 bayes_pls_golite062009
  • protein transporter activity
    		•  0.498432226280822 bayes_pls_golite062009
  • microtubule-severing ATPase activity
    		•  0.491769258942331 bayes_pls_golite062009
  • DNA binding
    		•  0.479412476059825 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.312171320541728 bayes_pls_golite062009
  • signal transducer activity
    		•  0.286367085584159 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.286367085584159 bayes_pls_golite062009
  • myosin binding
    		•  0.274885859454447 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  0.213018989352421 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  0.169034229773346 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.123304946374679 bayes_pls_golite062009
  • alpha-tubulin binding
    		•  0.100557713995661 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0775601177068852 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0111338193708552 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.0102645529518819 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle