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Protein Overview: GLMS_YERPE

General Information:
Name(s) found: GLMS_YERPE [Swiss-Prot]
Description(s) found:
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  • pir||AB0500 glutamine-fructose-6-phosphate transaminase (isomerizing) (EC 2.6.1.16) [imported] - Yersinia pestis (strain CO92) [NCBI NR]
  • gi|21759123|sp|Q8Z9S8.3|GLMS_YERPE RecName: Full=Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; AltName: Full=Hexosephosphate aminotransferase; AltName: Full=D-fructose-6-phosphate amidotransferase; AltName: Full=GFAT; AltName: Full=L-g [NCBI NR]
  • Glutamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Yersinia pestis GN=glmS PE=3 SV=3 [Swiss-Prot]
  • glucosamine--fructose-6-phosphate aminotransferase [Yersinia pseudotuberculosis IP 32953]gi|16124226|ref|NP_407539.1| glucosamine--fructose-6-phosphate aminotransferase [Yersinia pestis CO92]gi|45443748|ref|NP_995287.1| glucosamine--fructose-6-phosphate [nrdb_11152004_Chlamydomonas]
  • Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (Hexosephosphate aminotransferase) (D-fructose-6-phosphate amidotransferase) (GFAT) (L-glutamine-D-fructose-6-phosphate amidotransferase) (Glucosamine-6-phosphate synthase) [nr-271106-contam.fasta]
    • Organism: Yersinia pestis
    Length: 609 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGIVGAVAQ RDIAEILIEG LRRLEYRGYD SAGLAVVDSE GHLTRLRRVG KVHALSDAAE  60
   61 KQDLHGGTGI AHTRWATHGE PSEANAHPHV SDYISVVHNG IIENHEPLRE LLISRGYRFS 120
  121 SETDTEVIAH LVHWEQQQGG SLLEVVKRVI PQLRGAYGTV VMDSRDPSRL IAARSGSPLV 180
  181 IGCGVGENFI ASDQLALLPV TRRFIFLEEG DVVEVTRRSI SIFDKQGNAI ERPEIESQVQ 240
  241 YDAGDKGIYR HYMQKEIYEQ PMAIKNTLEG RLSHGMIDLS ELGPKADALL AEVQHIQIIA 300
  301 CGTSYNSGMV SRYWFESLAG VPCDVEIASE FRYRKSAVRP NSLLITLSQS GETADTLAAL 360
  361 RLSKELGYLG SLAICNVAGS SLVRESDLAL MTKAGTEIGV ASTKAFTTQL TVLLMLVGRI 420
  421 GKLKGADASL EHDIVHALQA LPARIEQMLS LDKTIEALAE GFSDKHHALF LGRGDQYPIA 480
  481 MEGALKLKEI SYIHAEAYAA GELKHGPLAL IDADMPVIVV APNNELLEKL KSNIEEVRAR 540
  541 GGLLYVFADQ DAGFTDSEGM KIIQLPHVEE IIAPIFYTVP LQLLSYHVAL IKGTDVDQPR 600
  601 NLAKSVTVE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..609] PSI-BLAST 167.0 "Isomerase domain" of glucosamine 6-phosphate synthase (GLMS); Glucosamine 6-phosphate synthase, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glutamine-fructose-6-phosphate transaminase (isomerizing) activity
    		•  4.12465195642555 bayes_pls_golite062009
  • glucose-6-phosphate isomerase activity
    		•  2.74527495029339 bayes_pls_golite062009
  • D-sedoheptulose 7-phosphate isomerase activity
    		•  2.03357282678145 bayes_pls_golite062009
  • intramolecular oxidoreductase activity
    		•  1.99606027864666 bayes_pls_golite062009
  • catalytic activity
    		•  1.5278037255884 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting aldoses and ketoses
    		•  1.49939040101274 bayes_pls_golite062009
  • sugar binding
    		•  1.40175307923331 bayes_pls_golite062009
  • peptidase activity
    		•  1.34295853726897 bayes_pls_golite062009
  • transferase activity
    		•  1.20219571915061 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.16226272745141 bayes_pls_golite062009
  • isomerase activity
    		•  0.875614547872629 bayes_pls_golite062009
  • binding
    		•  0.8320110584046 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.798789250029517 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.759765292911898 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  0.329741341879618 bayes_pls_golite062009
  • transaminase activity
    		•  0.307877519336205 bayes_pls_golite062009
  • protein binding
    		•  0.152745336606766 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle