YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: HGNC:9588|MIM:60...

General Information:
Name(s) found: HGNC:9588|MIM:601728|Ensembl:ENSG00000171862|HPRD:03431,HsxXG003565,H03,HsCD00305432,272718.0,pANT7_cGST,FUSION,NM_000314,5728.0,PTEN,10q23del|BZS|DEC|MGC11227|MHAM|MMAC1|PTEN1|TEP1,phosphatase [120926-122011-mus-fusion.fasta]
Description(s) found:
  • and tensin homolog [120926-122011-mus-fusion.fasta]
    • Organism: SPECIES UNKNOWN
    Length: 403 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAIIKEIVS RNKRRYQEDG FDLDLTYIYP NIIAMGFPAE RLEGVYRNNI DDVVRFLDSK  60
   61 HKNHYKIYNL CAERHYDTAK FNCRVAQYPF EDHNPPQLEL IKPFCEDLDQ WLSEDDNHVA 120
  121 AIHCKAGKGR TGVMICAYLL HRGKFLKAQE ALDFYGEVRT RDKKGVTIPS QRRYVYYYSY 180
  181 LLKNHLDYRP VALLFHKMMF ETIPMFSGGT CNPQFVVCQL KVKIYSSNSG PTRREDKFMY 240
  241 FEFPQPLPVC GDIKVEFFHK QNKMLKKDKM FHFWVNTFFI PGPEETSEKV ENGSLCDQEI 300
  301 DSICSIERAD NDKEYLVLTL TKNDLDKANK DKANRYFSPN FKVKLYFTKT VEEPSNPEAS 360
  361 SSTSVTPDVS DNEPDHYRYS DTTDSDPENE PFDEDQHTQI TKV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..403] PSI-BLAST 96.522879 Pten tumor suppressor (Phoshphoinositide phosphatase), C-terminal domain; Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  7.30669036331612 bayes_pls_golite062009
  • phosphatase activity
    		•  7.03758345564381 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.82821455971597 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.83769298632658 bayes_pls_golite062009
  • protein tyrosine phosphatase activity
    		•  5.3097342170423 bayes_pls_golite062009
  • lipid phosphatase activity
    		•  4.03975183132282 bayes_pls_golite062009
  • transmembrane receptor protein phosphatase activity
    		•  2.94635032478625 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine phosphatase activity
    		•  2.94635032478625 bayes_pls_golite062009
  • protein tyrosine/serine/threonine phosphatase activity
    		•  2.77531895423367 bayes_pls_golite062009
  • phosphatidylinositol-3-phosphatase activity
    		•  2.60529675907066 bayes_pls_golite062009
  • phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
    		•  2.16960414043368 bayes_pls_golite062009
  • inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
    		•  2.16960414043368 bayes_pls_golite062009
  • protein binding
    		•  2.12487185456363 bayes_pls_golite062009
  • binding
    		•  2.06015698112379 bayes_pls_golite062009
  • phosphatidylinositol trisphosphate phosphatase activity
    		•  2.05577133553311 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  1.95004535887255 bayes_pls_golite062009
  • phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
    		•  1.72084618199574 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.64963866171771 bayes_pls_golite062009
  • hydrolase activity
    		•  1.5596484415033 bayes_pls_golite062009
  • DNA binding
    		•  1.55311439718667 bayes_pls_golite062009
  • phosphatidylinositol bisphosphate phosphatase activity
    		•  1.51576958903553 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.19889854601141 bayes_pls_golite062009
  • inositol or phosphatidylinositol phosphatase activity
    		•  1.1200449509328 bayes_pls_golite062009
  • calcium-dependent phospholipid binding
    		•  1.06635493706319 bayes_pls_golite062009
  • catalytic activity
    		•  1.06283028154109 bayes_pls_golite062009
  • receptor activity
    		•  1.01393772058468 bayes_pls_golite062009
  • kinase activity
    		•  0.850298161488651 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.841726096794004 bayes_pls_golite062009
  • non-membrane spanning protein tyrosine phosphatase activity
    		•  0.724257798127697 bayes_pls_golite062009
  • phospholipase activity
    		•  0.689713182053935 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.667441519923463 bayes_pls_golite062009
  • protein kinase activity
    		•  0.569334963316149 bayes_pls_golite062009
  • SNARE binding
    		•  0.501334097212321 bayes_pls_golite062009
  • platelet-derived growth factor receptor binding
    		•  0.496312746149466 bayes_pls_golite062009
  • insulin receptor binding
    		•  0.33757017312249 bayes_pls_golite062009
  • neurexin binding
    		•  0.27749877320051 bayes_pls_golite062009
  • alpha-actinin binding
    		•  0.185193614037313 bayes_pls_golite062009
  • enzyme binding
    		•  0.150910330021054 bayes_pls_golite062009
  • kinase binding
    		•  0.141802531311128 bayes_pls_golite062009
  • phospholipase C activity
    		•  0.105085008317406 bayes_pls_golite062009
  • protein kinase binding
    		•  0.062562314598915 bayes_pls_golite062009
  • transferase activity
    		•  0.0332461821062801 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle