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Protein Overview: PRP5_YEAST

General Information:
Name(s) found: PRP5_YEAST [Swiss-Prot]
Description(s) found:
  • Pre-mRNA-processing ATP-dependent RNA helicase PRP5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRP5 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 849 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METIDSKQNI NRESLLEERR KKLAKWKQKK AQFDAQKEHQ TSRNDIVTNS LEGKQTTEKF  60
   61 TERQERVKEE LRKRKNEFRK SDEPVSVKPS KKKSKRSKVK KKISFDFSDD DDSEIGVSFR 120
  121 SKEHIQKAPE HDNEKDPLDE FMTSLKEEKM SNSKGMYDRG DILDVEDQLF ELGGTDDEDV 180
  181 EDNTDNSNIA KIAKLKAKKR VKQIYYSPEE LEPFQKNFYI ESETVSSMSE MEVEELRLSL 240
  241 DNIKIKGTGC PKPVTKWSQL GLSTDTMVLI TEKLHFGSLT PIQSQALPAI MSGRDVIGIS 300
  301 KTGSGKTISY LLPLLRQVKA QRPLSKHETG PMGLILAPTR ELALQIHEEV TKFTEADTSI 360
  361 RSVCCTGGSE MKKQITDLKR GTEIVVATPG RFIDILTLND GKLLSTKRIT FVVMDEADRL 420
  421 FDLGFEPQIT QIMKTVRPDK QCVLFSATFP NKLRSFAVRV LHSPISITIN SKGMVNENVK 480
  481 QKFRICHSED EKFDNLVQLI HERSEFFDEV QSENDGQSSD VEEVDAKAII FVSSQNICDF 540
  541 ISKKLLNAGI VTCAIHAGKP YQERLMNLEK FKREKNSILL CTEVLSRGLN VPEVSLVIIY 600
  601 NAVKTFAQYV HTTGRTARGS RSGTAITLLL HDELSGAYIL SKAMRDEEIK ALDPLQAKEL 660
  661 QEMSAKFESG MKKGKFRLSK GFGGKGLENI KSKREEAQNK DLELKKNDKR SDDLEKKISN 720
  721 PREGHDSVSE SSALIPRLNY ELFKESTDGS IIFYAKVYIN DLPQIVRWEA TKNTTLLFIK 780
  781 HETGCSITNK GKFYPEGKEP KNENDEPKLY LLIEGQDEKD IQLSIELLEQ KVKEGVVKAA 840
  841 SLSLKSTKY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..218] MSA 8.274997 View MSA. No confident structure predictions are available.
    2 View Details [219..278] PSI-BLAST 461.0 Initiation factor 4a
    3 View Details [279..473]
    [671..746]    		 PSI-BLAST 13.30103 RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain
    4 View Details [474..670] PSI-BLAST 13.30103 RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain
    5 View Details [747..849] ORFEUS 8.62 RNA splicing factor 1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • RNA binding
    		•  6.35205331138538 bayes_pls_golite062009
    		• 4.77327442333813 bayes_pls_golite062009
  • mRNA binding
    		•  4.67566555881601 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.53130750638836 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  3.73042056823822 bayes_pls_golite062009
  • translation regulator activity
    		•  3.73023228922019 bayes_pls_golite062009
  • binding
    		•  3.31439627344982 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.27014249542806 bayes_pls_golite062009
  • DNA binding
    		•  2.0152088603757 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  1.75736205236351 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.72867277839034 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.40423326576059 bayes_pls_golite062009
  • transcription factor activity
    		•  1.30878011063724 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  1.27324890490526 bayes_pls_golite062009
  • protein binding
    		•  1.09698608157472 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.925909354724523 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.795008427109843 bayes_pls_golite062009
  • hydrolase activity
    		•  0.715182212485288 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.370287528838428 bayes_pls_golite062009
  • transcription activator activity
    		•  0.281896115904289 bayes_pls_golite062009
  • transcription factor binding
    		•  0.207514957974522 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.150228013820667 bayes_pls_golite062009
  • catalytic activity
    		•  0.1435046019283 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.110425673333101 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0108102459345405 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle