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Protein Overview: RFA2_YEAST

General Information:
Name(s) found: RFA2_YEAST [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • Replication factor A protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RFA2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 273 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATYQPYNEY SSVTGGGFEN SESRPGSGES ETNTRVNTLT PVTIKQILES KQDIQDGPFV  60
   61 SHNQELHHVC FVGVVRNITD HTANIFLTIE DGTGQIEVRK WSEDANDLAA GNDDSSGKGY 120
  121 GSQVAQQFEI GGYVKVFGAL KEFGGKKNIQ YAVIKPIDSF NEVLTHHLEV IKCHSIASGM 180
  181 MKQPLESASN NNGQSLFVKD DNDTSSGSSP LQRILEFCKK QCEGKDANSF AVPIPLISQS 240
  241 LNLDETTVRN CCTTLTDQGF IYPTFDDNNF FAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..178] PSI-BLAST 142.69897 Replication protein A 32 KDa subunit (RPA32) fragment
    2 View Details [179..273] PSI-BLAST 25.69897 C-terminal domain of RPA32

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • telomeric DNA binding
    		•  7.07761964836826 bayes_pls_golite062009
  • single-stranded telomeric DNA binding
    		•  6.04637014849887 bayes_pls_golite062009
  • telomerase inhibitor activity
    		•  5.40477712257453 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.02967008021862 bayes_pls_golite062009
  • DNA binding
    		•  3.62735703519187 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  3.59212997362902 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  3.53214384646348 bayes_pls_golite062009
  • binding
    		•  2.63617204791771 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.25006883439646 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.20239961025491 bayes_pls_golite062009
  • structural molecule activity
    		•  2.07809455998137 bayes_pls_golite062009
  • DNA replication origin binding
    		•  1.84819558112187 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.19236946227657 bayes_pls_golite062009
  • DNA helicase activity
    		•  1.12203697857261 bayes_pls_golite062009
  • transcription factor activity
    		•  1.05816813143865 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.86170694706755 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.79554655100991 bayes_pls_golite062009
  • hydrolase activity
    		•  0.724860465280978 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.638831894247026 bayes_pls_golite062009
  • nuclease activity
    		•  0.57381531077345 bayes_pls_golite062009
  • DEAD/H-box RNA helicase binding
    		•  0.440977654731901 bayes_pls_golite062009
  • translation regulator activity
    		•  0.41164963411369 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.378383789953688 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.360862776629591 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.325774164899685 bayes_pls_golite062009
  • four-way junction helicase activity
    		•  0.31769813397725 bayes_pls_golite062009
  • RNA binding
    		•  0.31028563542112 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.30211828233765 bayes_pls_golite062009
  • exonuclease activity
    		•  0.28313884527829 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.226916777208049 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.223941674251642 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.125256208482441 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.109774918833391 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.0954216620147701 bayes_pls_golite062009
  • protein binding
    		•  0.0528188351789111 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.0179535526984695 bayes_pls_golite062009
  • helicase activity
    		•  0.0121541775159524 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle