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Protein Overview: RAD1_YEAST

General Information:
Name(s) found: RAD1_YEAST [Swiss-Prot]
Description(s) found:
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  • DNA repair protein RAD1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAD1 PE=1 SV=1 [Swiss-Prot]
  • Rad1p [Saccharomyces cerevisiae] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1100 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQLFYQGDS DDELQEELTR QTTQASQSSK IKNEDEPDDS NHLNEVENED SKVLDDDAVL  60
   61 YPLIPNEPDD IETSKPNIND IRPVDIQLTL PLPFQQKVVE NSLITEDALI IMGKGLGLLD 120
  121 IVANLLHVLA TPTSINGQLK RALVLVLNAK PIDNVRIKEA LEELSWFSNT GKDDDDTAVE 180
  181 SDDELFERPF NVVTADSLSI EKRRKLYISG GILSITSRIL IVDLLSGIVH PNRVTGMLVL 240
  241 NADSLRHNSN ESFILEIYRS KNTWGFIKAF SEAPETFVME FSPLRTKMKE LRLKNVLLWP 300
  301 RFRVEVSSCL NATNKTSHNK VIEVKVSLTN SMSQIQFGLM ECLKKCIAEL SRKNPELALD 360
  361 WWNMENVLDI NFIRSIDSVM VPNWHRISYE SKQLVKDIRF LRHLLKMLVT SDAVDFFGEI 420
  421 QLSLDANKPS VSRKYSESPW LLVDEAQLVI SYAKKRIFYK NEYTLEENPK WEQLIHILHD 480
  481 ISHERMTNHL QGPTLVACSD NLTCLELAKV LNASNKKRGV RQVLLNKLKW YRKQREETKK 540
  541 LVKEVQSQDT FPENATLNVS STFSKEQVTT KRRRTRGASQ VAAVEKLRNA GTNVDMEVVF 600
  601 EDHKLSEEIK KGSGDDLDDG QEENAANDSK IFEIQEQENE ILIDDGDAEF DNGELEYVGD 660
  661 LPQHITTHFN KDLWAEHCNE YEYVDRQDEI LISTFKSLND NCSLQEMMPS YIIMFEPDIS 720
  721 FIRQIEVYKA IVKDLQPKVY FMYYGESIEE QSHLTAIKRE KDAFTKLIRE NANLSHHFET 780
  781 NEDLSHYKNL AERKLKLSKL RKSNTRNAGG QQGFHNLTQD VVIVDTREFN ASLPGLLYRY 840
  841 GIRVIPCMLT VGDYVITPDI CLERKSISDL IGSLQNNRLA NQCKKMLKYY AYPTLLIEFD 900
  901 EGQSFSLEPF SERRNYKNKD ISTVHPISSK LSQDEIQLKL AKLVLRFPTL KIIWSSSPLQ 960
  961 TVNIILELKL GREQPDPSNA VILGTNKVRS DFNSTAKGLK DGDNESKFKR LLNVPGVSKI1020
 1021 DYFNLRKKIK SFNKLQKLSW NEINELINDE DLTDRIYYFL RTEKEEQEQE STDENLESPG1080
 1081 KTTDDNALHD HHNDVPEAPV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..299] PSI-BLAST 12.522879 Initiation factor 4a
    2 View Details [300..585] PSI-BLAST 3.0 RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain
    3 View Details [586..742] PSI-BLAST 3.0 RecG, N-terminal domain; RecG "wedge" domain; RecG helicase domain
    4 View Details [743..819] PSI-BLAST 28.0 Nucleotide excision repair enzyme UvrB
    5 View Details [820..989] PSI-BLAST 113.28043 Putative ATP-dependent RNA helicase Hef, nuclease domain
    6 View Details [990..1100] MSA 2.057993 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • single-stranded DNA specific endodeoxyribonuclease activity
    		•  12.5797089932289 bayes_pls_golite062009
  • endodeoxyribonuclease activity
    		•  7.65460057398582 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  6.8949486660401 bayes_pls_golite062009
  • endonuclease activity
    		•  6.81743235298471 bayes_pls_golite062009
  • four-way junction helicase activity
    		•  4.48421726286311 bayes_pls_golite062009
  • DNA helicase activity
    		•  4.45575761476577 bayes_pls_golite062009
  • DNA strand annealing activity
    		•  3.51692202399009 bayes_pls_golite062009
  • excinuclease ABC activity
    		•  3.48615352002265 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  3.44605832131927 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  3.37084035853131 bayes_pls_golite062009
  • damaged DNA binding
    		•  2.98078816242626 bayes_pls_golite062009
  • DNA binding
    		•  2.97855002479178 bayes_pls_golite062009
  • helicase activity
    		•  2.83648239124034 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.79236389919005 bayes_pls_golite062009
  • nuclease activity
    		•  2.20113675721212 bayes_pls_golite062009
  • binding
    		•  2.17324322139334 bayes_pls_golite062009
  • hydrolase activity
    		•  2.07039693890326 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.69645042781713 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  1.26255690081743 bayes_pls_golite062009
  • transposase activity
    		•  1.10140160488189 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.05548921907953 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.02983374615445 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.01049916010827 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.00920723797259 bayes_pls_golite062009
  • catalytic activity
    		•  0.816447099398022 bayes_pls_golite062009
  • protein binding
    		•  0.71091195096997 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle