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Protein Overview: gi|24417713

General Information:
Name(s) found: gi|24417713 [NCBI NR]
Description(s) found:
Found 3 descriptions.
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  • gi|24417713|gb|AAN60444.1| nesprin [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 2576 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDA]
    Z disc [IDA]
    cytoplasm [IDA]
    actin cytoskeleton [IDA]
    integrin complex [IDA]
    Biological Process: cytoskeleton organization [ISS]
    establishment of nucleus localization [IMP]
    skeletal muscle tissue development [IMP]
    mesoderm development [NAS]
    female germline ring canal stabilization [IMP]
    transcription from RNA polymerase II promoter [NAS]
    actin filament organization [IMP]
    cell migration [IMP]
    regulation of Rab GTPase activity [IEA]
    cytoplasmic transport, nurse cell to oocyte [IMP]
    Molecular Function: actin binding [IDA][ISS][NAS]
    RNA polymerase II transcription factor activity [NAS]
    double-stranded RNA binding [NAS]
    Rab GTPase activator activity [IEA]
    cytoskeletal protein binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLPKQEKKS KKDKKKKQKN VPEVEQQLPE DQQISVTVEI APELLSESGI VVSTNQQIED  60
   61 VPHVTPVVDT PIESEEVETP KAQRVQLQIT KTTVYDEYPD LPVHITEQNK VLIASQQSKR 120
  121 SGAGPTSSAV TIEEVGSPTE ELVVPITPGP DNLSGEPHNI WFSATTSVDK TPIELSQALI 180
  181 MSESLQHYPG QQKLTQEPIL ISTKEAIGDR IKQLKQASPQ QATPLSNVLH LATLSEQIKE 240
  241 LPTEQRILEV NEGLKDLDVA IKNGDKTVIQ TTVITVIEKV STWLETIEYR VYLIRQNSNE 300
  301 GPSEEKLDNY NQLNDELSTI KQNVVQLERQ LSKAEPEPQL LQCVDSLKEH VDAVEQVTQQ 360
  361 NQVQDSNDLD KWHNFEVLLY NVSSVLADLQ QSYDLLINQE YPLSAKLAQL DELEQQHEAA 420
  421 QQQLAHLCQN ARAFQRDFPG KKMPQDVHNA FETSKNIANN IQAERERVLQ LQSLAEEYEQ 480
  481 TLKEFTKITV LADKLVESPI VSSSLEQLNN EVQKQRKFFV NLSHCRAMLE SLEENIDSET 540
  541 REKHSELHKE LYNRATSLLD KASERSSKLV QAASRWTVLE KGMRDELQWL QVAQQRVPDL 600
  601 SAVTSADYDQ YTTLYQSLSN DISHHYVKMT QLSGIANKLQ LLVQAPNLVE ETNEALIVLL 660
  661 KLREEVALYL HRLLVFKEIW VQYEQQTDKL EAFVREAEQE LRNIQIPSQP THQPIEHMRQ 720
  721 FWEIKARFEL HNNVRTDTGL SFEKSLQVIP LADEMLQRQF HAQLEDRWQA VAQAIELIQH 780
  781 NIVECLSSED VPADEKLKMV ERELQEIYLT MTSMKGVIKN EEELCLYIER VQVLRTRVGF 840
  841 IGNELGRIGL QEPAIEPEKV GELFSLSHKI STQIAEELEG ASVLRDQLQA IQEGISNQRK 900
  901 HQAKISVILD ECEAAERQGA DVLEKAVADC QAAGEELVIS WQEIMRIRQM LHTLPMRLKM 960
  961 SVSPVKLERD ISQLQDDHAF LESKCTNIMA ILRSRLAVWL RYERQLELVH GSVQETDFMM1020
 1021 ELIRVHGQVD YERLRKATER LEGLAGDLHN REQLIDELKG AAKPLIESCD VQIVEQIESA1080
 1081 VQEAVVAWND TSENLQQLRT RYQRAVELWD KYRNASAAVK NSIDQQMDAV KSLEQPLDAL1140
 1141 QHAKVCQDNL TTQNDRILEL RDIVAKIAAD VGLDASALMQ GELDALGQRL AECKDAITTL1200
 1201 ANVAETQDKE RKELDKEVTL AKAYFNNVQQ DISREAPQNP KESEEQLAAL RAHLQTLART1260
 1261 EEQLRQLKER HQNSEVAPSV ASSDDDGILE VLALWQKIFQ DTFQEYHRLS TRLARSQNSS1320
 1321 EALRLWRQYL QHVQSFLSCA IPEDYSSLRE QQQLCAIHQN LLISQQSVLS ETPLESELSE1380
 1381 QYKALTNLHN ETLSRIMQRN GELERRVSGW NAYRQQLAAL LDWLRQREAE RNALQLRYIH1440
 1441 LKRVPHLKHR LDAMIQQLDQ GEQQSKALQE QQQELARHCD DALATAMRME QASIGQRISN1500
 1501 LRAALKTWQG FLQRVTQLSE SYEQRVNQLQ QEFGAAQKLL DANSESLPTQ PAAIEQLLGS1560
 1561 LRAQRVQLGA QVSALESLTV TQEELKECIS PHDMKTIRQR NWLLWQQHAD LDYQLANLIN1620
 1621 SIEERLSLLS NYQIRYDRIS QWLQRLEQRV EKDADVTAMT NPEQAAKQLE QQVNSELQLR1680
 1681 DKEREWLLST SRELLTLYSE PEVRSQVQQQ SDSLIDRWQR LKYLAKQKAT KIGELKMTLL1740
 1741 RLEERIALIR AWLFEVESQL DKPLNFESYT PNVIEAKLKE HEQIQRSIEH HSSNVGEVLN1800
 1801 LVEMLLNDAD SWRTQVNTSG LAASAQNLEQ RWKNVCSQSA ERKARILTIW NLLQQLIKLT1860
 1861 AEHKNWLGKQ ESQIAGFERD QKSHSKHKLE ERQMELRAKL EELESQSVNL RQLEQIYAKL1920
 1921 AMSAGVEPEN IQKLTLPTKV MVSMWRQLTP RCHALLDAID KDAKLMREFN NAQLEATNSL1980
 1981 NAIQKALEQL PSAENQQTSK AEPKAVLQRL ESLEKKLQDA QQHVQQADNL AQEAKTRTKQ2040
 2041 QPQLKQLLEL VSAYTTLWQT VQTRIVTLKT TWLTRAAQAA ASLPVSEAAN AAVQVNTLSQ2100
 2101 RKLRQAQQMQ RETSITAKDA YIMELQTAIT ECQNNLDELQ RTVVDKTRKP GPQKIAKLLG2160
 2161 NAQSSTELVK HLSHLLLTEC KADDQAAEVD TVAELTLRFD TLQSQWKARQ QHDQNASEVG2220
 2221 RLTCPLCTQR NWQQIDNDLW RLEQWLQFAE STQKAQSAPP SNIELLEDVT QDHREFLLDL2280
 2281 ESHKSIISSL NVVGDHLATH TLDTEKARQL RSRLEADNER WNNVCINATK WQGLLQTALM2340
 2341 GNSEFHQTIG ELVEWLQRTE QNIKASEPVD LTEERSVLET KFKKFKDLRA ELERCQPRVV2400
 2401 SLQDAADQLL RSVEGSEQQS QHTYERTLSR LTDLRLRLQS LRRLSGIYIV KLGAVLGYEG2460
 2461 DNLGVPLHML SSELLDNTTL STSSMQAAAP NTENANNTDG GDAVDGDVIN TTVLARGARF2520
 2521 LGRVARASLP IQALMLLLLG VATLVPHGED YTCMFSNTFA RSLEPMLSYP HGPPPT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle