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Protein Overview: SWH1

General Information:
Name(s) found: SWH1 / YAR042W [SGD]
Description(s) found:
Found 15 descriptions.
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  • Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats; localizes to the Golgi and the nucleus-vacuole junction [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1188 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    early endosome [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Golgi trans cisterna [IDALink to PubMed article]
    Biological Process: sterol transport [IGILink to PubMed article]
    endocytosis [IGILink to PubMed article]
    exocytosis [IGILink to PubMed article]
    Molecular Function: oxysterol binding [ISSLink to PubMed article]
    phosphatidylinositol binding [ISSLink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQPDLSSVA ISKPLLKLKL LDALRQGSFP NLQDLLKKQF QPLDDPNVQQ VLHLMLHYAV  60
   61 QVAPMAVIKE IVHHWVSTTN TTFLNIHLDL NERDSNGNTP LHIAAYQSRG DIVAFLLDQP 120
  121 TINDCVLNNS HLQAIEMCKN LNIAQMMQVK RSTYVAETAQ EFRTAFNNRD FGHLESILSS 180
  181 PRNAELLDIN GMDPETGDTV LHEFVKKRDV IMCRWLLEHG ADPFKRDRKG KLPIELVRKV 240
  241 NENDTATNTK IAIDIELKKL LERATREQSV IDVTNNNLHE APTYKGYLKK WTNFAQGYKL 300
  301 RWFILSSDGK LSYYIDQADT KNACRGSLNM SSCSLHLDSS EKLKFEIIGG NNGVIRWHLK 360
  361 GNHPIETNRW VWAIQGAIRY AKDREILLHN GPYSPSLALS HGLSSKVSNK ENLHATSKRL 420
  421 TKSPHLSKST LTQNDHDNDD DSTNNNNNKS NNDYDDNNNN NNNDDDDYDD DDESRPLIEP 480
  481 LPLISSRSQS LSEITPGPHS RKSTVSSTRA ADIPSDDEGY SEDDSDDDGN SSYTMENGGE 540
  541 NDGDEDLNAI YGPYIQKLHM LQRSISIELA SLNELLQDKQ QHDEYWNTVN TSIETVSEFF 600
  601 DKLNRLTSQR EKRMIAQMTK QRDVNNVWIQ SVKDLEMELV DKDEKLVALD KERKNLKKML 660
  661 QKKLNNQPQV ETEANEESDD ANSMIKGSQE STNTLEEIVK FIEATKESDE DSDADEFFDA 720
  721 EEAASDKKAN DSEDLTTNKE TPANAKPQEE APEDESLIVI SSPQVEKKNQ LLKEGSFVGY 780
  781 EDPVRTKLAL DEDNRPKIGL WSVLKSMVGQ DLTKLTLPVS FNEPTSLLQR VSEDIEYSHI 840
  841 LDQAATFEDS SLRMLYVAAF TASMYASTTN RVSKPFNPLL GETFEYARTD GQYRFFTEQV 900
  901 SHHPPISATW TESPKWDFYG ECNVDSSFNG RTFAVQHLGL WYITIRPDHN ISVPEETYSW 960
  961 KKPNNTVIGI LMGKPQVDNS GDVKVTNHTT GDYCMLHYKA HGWTSAGAYE VRGEVFNKDD1020
 1021 KKLWVLGGHW NDSIYGKKVT ARGGELTLDR IKTANSATGG PKLDGSKFLI WKANERPSVP1080
 1081 FNLTSFALTL NALPPHLIPY LAPTDSRLRP DQRAMENGEY DKAAAEKHRV EVKQRAAKKE1140
 1141 REQKGEEYRP KWFVQEEHPV TKSLYWKFNG EYWNKRKNHD FKDCADIF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) OSH2 SWH1
    View Details Krogan NJ, et al. (2006) OSH2 SWH1
    View Details Gavin AC, et al. (2002) FKS1 NUM1 OPI1 OSH2 PIL1 RPN10 SCS2 STT4 SWH1 YAR044W
    View Details Qiu et al. (2008) KES1 OSH2 SWH1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SWH1 Huh WK, et al. (2003)

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle