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Protein Overview: NDUS1_ARATH

General Information:
Name(s) found: NDUS1_ARATH [Swiss-Prot]
Description(s) found:
Found 12 descriptions.
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  • NADH dehydrogenase [ubiquinone] iron-sulfur protein 1, mitochondrial OS=Arabidopsis thaliana GN=EMB1467 PE=1 SV=2 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 748 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IDA]
    mitochondrial respiratory chain complex I [IDA]
    mitochondrial membrane [IDA]
    respiratory chain complex I [IDA]
    mitochondrion [IDA]
    Biological Process: response to oxidative stress [IDA]
    embryonic development ending in seed dormancy [NAS]
    photorespiration [TAS]
    Molecular Function: NADH dehydrogenase activity [ISS]
    oxidoreductase activity [IEA]
    electron carrier activity [IEA]
    NADH dehydrogenase (ubiquinone) activity [IEA]
    oxidoreductase activity, acting on NADH or NADPH [IEA]
    iron-sulfur cluster binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLGILASRT IRPASRLLQS QTSNFFLRTI VSKPELQSPE SAAVSEPEPP TQILPPRNPV  60
   61 GGARVHFSNP EDAIEVFVDG YAVKVPKGFT VLQACEVAGV DIPRFCYHSR LSIAGNCRMC 120
  121 LVEVEKSPKP VASCAMPALP GMKIKTDTPI AKKAREGVME FLLMNHPLDC PICDQGGECD 180
  181 LQDQSMAFGS DRGRFTEMKR SVVDKNLGPL VKTVMTRCIQ CTRCVRFASE VAGVQDLGIL 240
  241 GRGSGEEIGT YVEKLMTSEL SGNVIDICPV GALTSKPFAF KARNWELKAT ETIDVSDAVG 300
  301 SNIRVDSRGP EVMRIIPRLN EDINEEWISD KTRFCYDGLK RQRLSDPMIR DSDGRFKAVS 360
  361 WRDALAVVGD IIHQVKPDEI VGVAGQLSDA ESMMVLKDFV NRMGSDNVWC EGTAAGVDAD 420
  421 LRYSYLMNTS ISGLENADLF LLIGTQPRVE AAMVNARICK TVRASNAKVG YVGPPAEFNY 480
  481 DCKHLGTGPD TLKEIAEGRH PFCTALKNAK NPAIIVGAGL FNRTDKNAIL SSVESIAQAN 540
  541 NVVRPDWNGL NFLLQYAAQA AALDLGLIQQ SAKALESAKF VYLMGADDVN VDKIPKDAFV 600
  601 VYQGHHGDKA VYRANVILPA SAFTEKEGTY ENTEGFTQQT VPAVPTVGDA RDDWKIVRAL 660
  661 SEVSGVKLPY NSIEGVRSRI KSVAPNLVHT DEREPAAFGP SLKPECKEAM STTPFQTVVE 720
  721 NFYMTNSITR ASKIMAQCSA VLLKKPFV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..71] PSI-BLAST 12.30103 PHTHALATE DIOXYGENASE REDUCTASE: A MODULAR STRUCTURE FOR ELECTRON TRANSFER FROM PYRIDINE NUCLEOTIDES TO [2FE-2S]
    2 View Details [72..748] PSI-BLAST 94.0 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • NADH dehydrogenase activity
    		•  8.57020397959255 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  8.38566609923386 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  8.21082857163161 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  7.52220758347541 bayes_pls_golite062009
  • oxidoreductase activity
    		•  7.16286065347789 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  7.03780998761655 bayes_pls_golite062009
  • formate dehydrogenase activity
    		•  4.68407412780362 bayes_pls_golite062009
  • 4 iron, 4 sulfur cluster binding
    		•  3.54243134597505 bayes_pls_golite062009
  • oxidoreduction-driven active transmembrane transporter activity
    		•  3.29174700910768 bayes_pls_golite062009
  • succinate dehydrogenase activity
    		•  3.27019699125535 bayes_pls_golite062009
  • electron carrier activity
    		•  2.86867645862628 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  2.73204059194206 bayes_pls_golite062009
  • metal cluster binding
    		•  2.57357653703854 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  2.57357653703854 bayes_pls_golite062009
  • nitrate reductase activity
    		•  2.20600951698793 bayes_pls_golite062009
  • catalytic activity
    		•  1.93875927205186 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor
    		•  1.87673954208357 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  1.84836110501265 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  1.54181416413094 bayes_pls_golite062009
  • oxidoreductase activity, acting on other nitrogenous compounds as donors
    		•  1.12492792673137 bayes_pls_golite062009
  • binding
    		•  1.0770649921334 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  0.737415967372169 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  0.67478911167421 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.614505320206825 bayes_pls_golite062009
  • ferrous iron binding
    		•  0.599635746381861 bayes_pls_golite062009
  • cation binding
    		•  0.292059992813768 bayes_pls_golite062009
  • metal ion binding
    		•  0.292059992813768 bayes_pls_golite062009
  • ion binding
    		•  0.285849308897776 bayes_pls_golite062009
  • protein binding
    		•  0.128023487683923 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle