Protein Overview: KU70_ARATH

General Information:
Name(s) found:	KU70_ARATH [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|62320632\|dbj\|BAD95294.1\| Ku70-like protein [Arabidopsis thaliana] [NCBI NR] gi\|18394425\|ref\|NP_564012.1\| KU70 (ARABIDOPSIS THALIANA KU70 HOMOLOG); double-stranded DNA binding / protein binding [Arabidopsis thaliana] [NCBI NR] gi\|12006424\|gb\|AAG44852.1\|AF283759_1 Ku70-like protein [Arabidopsis thaliana] [NCBI NR] ATP-dependent DNA helicase 2 subunit KU70 OS=Arabidopsis thaliana GN=KU70 PE=1 SV=1 [Swiss-Prot] Ku70-like protein [Arabidopsis thaliana]gi\|18394425\|ref\|NP_564012.1\| Ku70-like protein [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas] Tax_Id=3702 Ku70-like protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta] \| Symbols: KU70, ATKU70 \| ATKU70/KU70 (ARABIDOPSIS THALIANA KU70 HOMOLOG); double-stranded DNA binding / protein binding \| chr1:5801152-5805717 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta] Ku70-like protein [Arabidopsis thaliana] [nr-271106-contam.fasta] KU70 [Arabidopsis thaliana] [nr-271106-contam.fasta] \| Symbols: KU70, ATKU70 \| KU70 homolog \| chr1:5801159-5805724 REVERSE LENGTH=621 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
Organism:	Arabidopsis thaliana
Length:	621 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] DNA-dependent protein kinase-DNA ligase 4 complex [IEA]
Biological Process:	DNA repair [TAS] response to heat [IEP] telomere maintenance [TAS]
Molecular Function:	protein binding [IPI] double-stranded DNA binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELDPDDVFR DEDEDPENDF FQEKEASKEF VVYLIDASPK MFCSTCPSEE EDKQESHFHI  60
   61 AVSCIAQSLK AHIINRSNDE IAICFFNTRE KKNLQDLNGV YVFNVPERDS IDRPTARLIK 120
  121 EFDLIEESFD KEIGSQTGIV SDSRENSLYS ALWVAQALLR KGSLKTADKR MFLFTNEDDP 180
  181 FGSMRISVKE DMTRTTLQRA KDAQDLGISI ELLPLSQPDK QFNITLFYKD LIGLNSDELT 240
  241 EFMPSVGQKL EDMKDQLKKR VLAKRIAKRI TFVICDGLSI ELNGYALLRP AIPGSITWLD 300
  301 STTNLPVKVE RSYICTDTGA IMQDPIQRIQ PYKNQNIMFT VEELSQVKRI STGHLRLLGF 360
  361 KPLSCLKDYH NLKPSTFLYP SDKEVIGSTR AFIALHRSMI QLERFAVAFY GGTTPPRLVA 420
  421 LVAQDEIESD GGQVEPPGIN MIYLPYANDI RDIDELHSKP GVAAPRASDD QLKKASALMR 480
  481 RLELKDFSVC QFANPALQRH YAILQAIALD ENELRETRDE TLPDEEGMNR PAVVKAIEQF 540
  541 KQSIYGDDPD EESDSGAKEK SKKRKAGDAD DGKYDYIELA KTGKLKDLTV VELKTYLTAN 600
  601 NLLVSGKKEV LINRILTHIG K

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
double-stranded telomeric DNA binding	8.64621483095491	bayes_pls_golite062009
DNA-dependent protein kinase activity	7.33495559751688	bayes_pls_golite062009
telomeric DNA binding	5.16364366157397	bayes_pls_golite062009
transcription regulator activity	3.05720838352689	bayes_pls_golite062009
promoter binding	3.01492777192913	bayes_pls_golite062009
transcription activator activity	2.87080577911324	bayes_pls_golite062009
binding	2.75824485094584	bayes_pls_golite062009
protein binding	2.58357303743968	bayes_pls_golite062009
nucleic acid binding	2.08531850924748	bayes_pls_golite062009
DNA binding	1.91667917801679	bayes_pls_golite062009
transcription repressor activity	1.69798374416156	bayes_pls_golite062009
transcription factor activity	1.37299910766941	bayes_pls_golite062009
DNA-dependent ATPase activity	0.985753648509262	bayes_pls_golite062009
protein complex binding	0.94234534987624	bayes_pls_golite062009
sequence-specific DNA binding	0.914051610867509	bayes_pls_golite062009
single-stranded DNA binding	0.814975395718076	bayes_pls_golite062009
protein dimerization activity	0.73404855126602	bayes_pls_golite062009
DNA helicase activity	0.720743494912414	bayes_pls_golite062009
transcription corepressor activity	0.702777559747981	bayes_pls_golite062009
protein heterodimerization activity	0.64812784969409	bayes_pls_golite062009
ATP-dependent DNA helicase activity	0.506640285146188	bayes_pls_golite062009
structure-specific DNA binding	0.450760554291027	bayes_pls_golite062009
structural molecule activity	0.375125487765613	bayes_pls_golite062009
receptor binding	0.234020194580985	bayes_pls_golite062009
transcription factor binding	0.184852480703492	bayes_pls_golite062009
protein C-terminus binding	0.15516806759612	bayes_pls_golite062009
identical protein binding	0.125363466534611	bayes_pls_golite062009
collagen binding	0.113837148027681	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..621]	PSI-BLAST	157.0	DNA binding C-terminal domain of ku70; Ku70 subunit

Protein Overview: KU70_ARATH

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: