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Protein Overview: tba-8

General Information:
Name(s) found: tba-8 / CE37468 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00006534 locus:tba-8 Tubulin alpha-8 chain status:Partially_confirmed UniProt:P52274 protein_id:CAA85497.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 452 amino acids

    Gene Ontology:
    Cellular Component: protein complex [IEALink to PubMed article]
    microtubule [IEALink to PubMed article]
    Biological Process: protein polymerization [IEALink to PubMed article]
    microtubule-based process [IEALink to PubMed article]
    Molecular Function: GTP binding [IEALink to PubMed article]
    GTPase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSDGRECVS IHIGQAGAQI GNACWELYCI EHGLDEAGFL KEEEKNKKQQ SLQAFFSESM  60
   61 NGKHVPRAIY VDLEPTVLDE IRNGVYGNLF HPDQIINGKE DAANNYARGH YTIGKELIDV 120
  121 VLDRIRKQTE NCEGLQGFLV FHSFGGGTGS GFSSLLMERL SVEFGKKSKL EFSVYPAPQV 180
  181 STSVVEPYNS ILTTHTTLEL SDCSFMVDNE AIYDLCRQKL HVERPSYSNL NRLIAQVVSS 240
  241 ITASLRFDGA LNVDLNEFQT NLVPYPRIHF PLATYAPVIS ADRAHHEPLS VQDITHMCFE 300
  301 KANQMVKCDP SAGKYMAVCL LYRGDVVPKD VNAAISSVKA KRGINFVDWC PTGFKVGINY 360
  361 QAPITVEGGD LAKVHRAVCM LSNTTAIAEA WARLDHKFDL MYSKRAFVHW FVGEGMEEGE 420
  421 FMEARDDLAA LEKDYAEVSR DTADLEEEND EF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..452] PSI-BLAST 176.0 Tubulin-colchicine-vinblastine: stathmin-like domain complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • structural constituent of cytoskeleton
    		•  4.04224160177678 bayes_pls_golite062009
  • structural molecule activity
    		•  3.32779015200848 bayes_pls_golite062009
  • tubulin binding
    		•  2.4432045213385 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.24606230377981 bayes_pls_golite062009
  • binding
    		•  2.00508289492248 bayes_pls_golite062009
  • GTPase activity
    		•  1.87512665946067 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.77500173070686 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.7017047947554 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.68267378160702 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.68038087466376 bayes_pls_golite062009
  • protein binding
    		•  1.60795853516357 bayes_pls_golite062009
  • MHC class I protein binding
    		•  1.46574865275013 bayes_pls_golite062009
  • gamma-tubulin binding
    		•  1.02742779831447 bayes_pls_golite062009
  • hydrolase activity
    		•  0.502038132260603 bayes_pls_golite062009
  • receptor binding
    		•  0.00945891657658993 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle