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View Structure Prediction Details

Protein: tba-8
Organism: Caenorhabditis elegans
Length: 452 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tba-8.

Description E-value Query
Range
Subject
Range
TBA_XENLA - (P08537) Tubulin alpha chain
616.0 [0..5] [452..1]

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Predicted Domain #1
Region A:
Residues: [1-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSDGRECVS IHIGQAGAQI GNACWELYCI EHGLDEAGFL KEEEKNKKQQ SLQAFFSESM  60
   61 NGKHVPRAIY VDLEPTVLDE IRNGVYGNLF HPDQIINGKE DAANNYARGH YTIGKELIDV 120
  121 VLDRIRKQTE NCEGLQGFLV FHSFGGGTGS GFSSLLMERL SVEFGKKSKL EFSVYPAPQV 180
  181 STSVVEPYNS ILTTHTTLEL SDCSFMVDNE AIYDLCRQKL HVERPSYSNL NRLIAQVVSS 240
  241 ITASLRFDGA LNVDLNEFQT NLVPYPRIHF PLATYAPVIS ADRAHHEPLS VQDITHMCFE 300
  301 KANQMVKCDP SAGKYMAVCL LYRGDVVPKD VNAAISSVKA KRGINFVDWC PTGFKVGINY 360
  361 QAPITVEGGD LAKVHRAVCM LSNTTAIAEA WARLDHKFDL MYSKRAFVHW FVGEGMEEGE 420
  421 FMEARDDLAA LEKDYAEVSR DTADLEEEND EF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 176.0
Match: 1z2bA
Description: Tubulin-colchicine-vinblastine: stathmin-like domain complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural constituent of cytoskeleton 4.04224160177678 bayes_pls_golite062009
structural molecule activity 3.32779015200848 bayes_pls_golite062009
tubulin binding 2.4432045213385 bayes_pls_golite062009
cytoskeletal protein binding 2.24606230377981 bayes_pls_golite062009
binding 2.00508289492248 bayes_pls_golite062009
GTPase activity 1.87512665946067 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.77500173070686 bayes_pls_golite062009
pyrophosphatase activity 1.7017047947554 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.68267378160702 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.68038087466376 bayes_pls_golite062009
protein binding 1.60795853516357 bayes_pls_golite062009
MHC class I protein binding 1.46574865275013 bayes_pls_golite062009
gamma-tubulin binding 1.02742779831447 bayes_pls_golite062009
hydrolase activity 0.502038132260603 bayes_pls_golite062009
receptor binding 0.00945891657658993 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle