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Protein Overview: gi|27228264, gi|...

General Information:
Name(s) found: gi|27228264 [NCBI NR]
gi|25012306 [NCBI NR]
gi|116008058 [NCBI NR]
gi|113194807 [NCBI NR]
Description(s) found:
Found 12 descriptions.
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  • gi|27228264|gb|AAN85717.1| loechrig isoform IV [Drosophila melanogaster] [NCBI NR]
  • gi|25012306|gb|AAN71265.1| LD41424p [Drosophila melanogaster] [NCBI NR]
  • gi|116008058|ref|NP_001036736.1| SNF4/AMP-activated protein kinase gamma subunit, isoform L [Drosophila melanogaster] [NCBI NR]
  • gi|113194807|gb|ABI31187.1| SNF4/AMP-activated protein kinase gamma subunit, isoform L [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 718 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: positive regulation of cell cycle [IGI]
    protein amino acid phosphorylation [ISS]
    cholesterol homeostasis [IMP]
    Molecular Function: AMP-activated protein kinase activity [ISS][NAS]
    protein serine/threonine kinase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNNGPTASS NYQLLNSANL RDLIDGQRHS HHVSRRDDSQ SHSHSESPSH IGHISQSNQS  60
   61 IPSLPSLPSG KNKTKDGKKL KATLTAAMSS SLLRRKAHSN HSQQQKLQLQ QQQQEQHQQQ 120
  121 LQQQQLRSNN SKAIANAARH SLGHSPSAAA AAAAVQQTLV YERRRVSSAH SSPSPTSRHH 180
  181 SPVHQCMLMR RRSDYSVEQI EQWKRQQQLL PRSGRKISLP VADPFLEKVN LSDLEEDDSQ 240
  241 IFVKFFRFHK CYDLIPTSAK LVVFDTQLLV KKAFYALVYN GVRAAPLWDS EKQQFVGMLT 300
  301 ITDFIKILQM YYKSPNASME QLEEHKLDTW RSVLHNQVMP LVSIGPDASL YDAIKILIHS 360
  361 RIHRLPVIDP ATGNVLYILT HKRILRFLFL YINELPKPAY MQKSLRELKI GTYNNIETAD 420
  421 ETTSIITALK KFVERRVSAL PLVDSDGRLV DIYAKFDVIN LAAEKTYNDL DVSLRKANEH 480
  481 RNEWFEGVQK CNLDESLYTI MERIVRAEVH RLVVVDENRK VIGIISLSDI LLYLVLRPSG 540
  541 EGVGGSESSL RASDPVLLRK VAEVEIPATA AAATTTTPPR SPSAGSGNRS LIEDIPEEET 600
  601 APARSDDADS DNNKSASEDK ANNNQHDQTT TAATANGDSN NSPVEVSFAD EAQEEEAADQ 660
  661 VERSNCDDDD QPALAEIERK NASMDDDEDD GMSSAVSAAS ALGQSLTPAA QEMALVSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..230] MSA 4.401996 View MSA. No confident structure predictions are available.
    2 View Details [231..336] PSI-BLAST 50.0 No description for 2v8qE was found.
    3 View Details [337..392] FFAS03 2.51 Crystal structure of CBS domain-containing predicted protein (TM0935) from Thermotoga maritima at 1.87 A resolution
    4 View Details [393..535] PSI-BLAST 19.221849 No description for 2uv6A was found.
    5 View Details [536..718] PSI-BLAST 18.522879 Structure of human guanosine monophosphate reductase GMPR1 in complex with GMP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • phosphorylase kinase regulator activity
    		•  7.70391834244316 bayes_pls_golite062009
  • AMP-activated protein kinase activity
    		•  7.44642435115105 bayes_pls_golite062009
  • cAMP-dependent protein kinase inhibitor activity
    		•  6.93689873566354 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  2.56838904228494 bayes_pls_golite062009
  • protein kinase activity
    		•  2.52567871323046 bayes_pls_golite062009
  • kinase activity
    		•  2.4422214009645 bayes_pls_golite062009
  • cAMP-dependent protein kinase regulator activity
    		•  2.35874140792742 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.34602478412267 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  2.17402447573866 bayes_pls_golite062009
  • transferase activity
    		•  1.64817967293013 bayes_pls_golite062009
  • binding
    		•  1.63354691422982 bayes_pls_golite062009
  • protein binding
    		•  1.38803085961368 bayes_pls_golite062009
  • protein kinase binding
    		•  1.35253529418057 bayes_pls_golite062009
  • kinase binding
    		•  1.3320291155323 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  1.31002370375073 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.26281943988481 bayes_pls_golite062009
  • ion channel activity
    		•  0.956667854360503 bayes_pls_golite062009
  • channel activity
    		•  0.940842319076591 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.940842319076591 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.929686668465826 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.889901921302766 bayes_pls_golite062009
  • gated channel activity
    		•  0.736786411102643 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.709718817747483 bayes_pls_golite062009
  • enzyme binding
    		•  0.263336937308997 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  0.254655971647361 bayes_pls_golite062009
  • kinase regulator activity
    		•  0.22192900867037 bayes_pls_golite062009
  • catalytic activity
    		•  0.205284274859133 bayes_pls_golite062009
  • PDZ domain binding
    		•  0.0288055199494393 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  0.00255895098457382 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle