YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|27228264, gi|...
Organism: Drosophila melanogaster
Length: 718 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|27228264, gi|....

Description E-value Query
Range
Subject
Range
gi|220950704 - gi|220950704|gb|ACL87895.1| SNF4Agamma-PG [synthetic construct]
SNF4Agamma-PG - The gene SNF4/AMP-activated protein kinase gamma subunit is referred to in FlyBase by the symbol Dme...
353.0 [0..1] [718..97]

Back

Predicted Domain #1
Region A:
Residues: [1-230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNNGPTASS NYQLLNSANL RDLIDGQRHS HHVSRRDDSQ SHSHSESPSH IGHISQSNQS  60
   61 IPSLPSLPSG KNKTKDGKKL KATLTAAMSS SLLRRKAHSN HSQQQKLQLQ QQQQEQHQQQ 120
  121 LQQQQLRSNN SKAIANAARH SLGHSPSAAA AAAAVQQTLV YERRRVSSAH SSPSPTSRHH 180
  181 SPVHQCMLMR RRSDYSVEQI EQWKRQQQLL PRSGRKISLP VADPFLEKVN 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [231-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSDLEEDDSQ IFVKFFRFHK CYDLIPTSAK LVVFDTQLLV KKAFYALVYN GVRAAPLWDS  60
   61 EKQQFVGMLT ITDFIKILQM YYKSPNASME QLEEHKLDTW RSVLHN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.0
Match: 2v8qE
Description: No description for 2v8qE was found.

Predicted Domain #3
Region A:
Residues: [337-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVMPLVSIGP DASLYDAIKI LIHSRIHRLP VIDPATGNVL YILTHKRILR FLFLYI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.51
Match: 1o50A
Description: Crystal structure of CBS domain-containing predicted protein (TM0935) from Thermotoga maritima at 1.87 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphorylase kinase regulator activity 7.70391834244316 bayes_pls_golite062009
AMP-activated protein kinase activity 7.44642435115105 bayes_pls_golite062009
cAMP-dependent protein kinase inhibitor activity 6.93689873566354 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 2.56838904228494 bayes_pls_golite062009
protein kinase activity 2.52567871323046 bayes_pls_golite062009
kinase activity 2.4422214009645 bayes_pls_golite062009
cAMP-dependent protein kinase regulator activity 2.35874140792742 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.34602478412267 bayes_pls_golite062009
protein serine/threonine kinase activity 2.17402447573866 bayes_pls_golite062009
transferase activity 1.64817967293013 bayes_pls_golite062009
binding 1.63354691422982 bayes_pls_golite062009
protein binding 1.38803085961368 bayes_pls_golite062009
protein kinase binding 1.35253529418057 bayes_pls_golite062009
kinase binding 1.3320291155323 bayes_pls_golite062009
substrate-specific channel activity 1.31002370375073 bayes_pls_golite062009
ion transmembrane transporter activity 1.26281943988481 bayes_pls_golite062009
ion channel activity 0.956667854360503 bayes_pls_golite062009
channel activity 0.940842319076591 bayes_pls_golite062009
passive transmembrane transporter activity 0.940842319076591 bayes_pls_golite062009
metal ion transmembrane transporter activity 0.929686668465826 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.889901921302766 bayes_pls_golite062009
gated channel activity 0.736786411102643 bayes_pls_golite062009
cation transmembrane transporter activity 0.709718817747483 bayes_pls_golite062009
enzyme binding 0.263336937308997 bayes_pls_golite062009
protein kinase regulator activity 0.254655971647361 bayes_pls_golite062009
kinase regulator activity 0.22192900867037 bayes_pls_golite062009
catalytic activity 0.205284274859133 bayes_pls_golite062009
PDZ domain binding 0.0288055199494393 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 0.00255895098457382 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [393-535]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NELPKPAYMQ KSLRELKIGT YNNIETADET TSIITALKKF VERRVSALPL VDSDGRLVDI  60
   61 YAKFDVINLA AEKTYNDLDV SLRKANEHRN EWFEGVQKCN LDESLYTIME RIVRAEVHRL 120
  121 VVVDENRKVI GIISLSDILL YLV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.221849
Match: 2uv6A
Description: No description for 2uv6A was found.

Predicted Domain #5
Region A:
Residues: [536-718]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRPSGEGVGG SESSLRASDP VLLRKVAEVE IPATAAAATT TTPPRSPSAG SGNRSLIEDI  60
   61 PEEETAPARS DDADSDNNKS ASEDKANNNQ HDQTTTAATA NGDSNNSPVE VSFADEAQEE 120
  121 EAADQVERSN CDDDDQPALA EIERKNASMD DDEDDGMSSA VSAASALGQS LTPAAQEMAL 180
  181 VSE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.522879
Match: 2bleA
Description: Structure of human guanosine monophosphate reductase GMPR1 in complex with GMP
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle