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Protein Overview: SNF4Agamma-PG

General Information:
Name(s) found: SNF4Agamma-PG / FBpp0083427 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene SNF4/AMP-activated protein kinase gamma subunit is referred to in FlyBase by the symbol Dmel\SNF4AÃ?&#142;Ã?³ (CG17299, FBgn0025803). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16966463..17038409. It has the cytological map location 93C1-93C5. Based on sequence similarity, it is predicted to have molecular function</span>: AMP-activated protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of cell cycle; cholesterol homeostasis. 51 alleles are reported. The phenotypes of these alleles are annotated with: adult central complex; trichogen cell; adult central nervous system; tormogen cell; adult brain. It has 16 annotated transcripts and 16 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 814 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: positive regulation of cell cycle [IGI]
    protein amino acid phosphorylation [ISS]
    cholesterol homeostasis [IMP]
    Molecular Function: AMP-activated protein kinase activity [ISS][NAS]
    protein serine/threonine kinase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYRRRYSAFE PSTPRVGVLP SPPPQYANPP ADTAAPKTPP KLSVHFDPNL PKDNDSNNNL  60
   61 TGSENANAKG GGRKARSLSN SPLYHRKKRY GHLPALMSNN GPTASSNYQL LNSANLRDLI 120
  121 DGQRHSHHVS RRDDSQSHSH SESPSHIGHI SQSNQSIPSL PSLPSGKNKT KDGKKLKATL 180
  181 TAAMSSSLLR RKAHSNHSQQ QKLQLQQQQQ EQHQQQLQQQ QLRSNNSKAI ANAARHSLGH 240
  241 SPSAAAAAAA VQQTLVYERR RVSSAHSSPS PTSRHHSPVH QCMLMRRRSD YSVEQIEQWK 300
  301 RQQQLLPRSG RKISLPVADP FLEKVNLSDL EEDDSQIFVK FFRFHKCYDL IPTSAKLVVF 360
  361 DTQLLVKKAF YALVYNGVRA APLWDSEKQQ FVGMLTITDF IKILQMYYKS PNASMEQLEE 420
  421 HKLDTWRSVL HNQVMPLVSI GPDASLYDAI KILIHSRIHR LPVIDPATGN VLYILTHKRI 480
  481 LRFLFLYINE LPKPAYMQKS LRELKIGTYN NIETADETTS IITALKKFVE RRVSALPLVD 540
  541 SDGRLVDIYA KFDVINLAAE KTYNDLDVSL RKANEHRNEW FEGVQKCNLD ESLYTIMERI 600
  601 VRAEVHRLVV VDENRKVIGI ISLSDILLYL VLRPSGEGVG GSESSLRASD PVLLRKVAEV 660
  661 EIPATAAAAT TTTPPRSPSA GSGNRSLIED IPEEETAPAR SDDADSDNNK SASEDKANNN 720
  721 QHDQTTTAAT ANGDSNNSPV EVSFADEAQE EEAADQVERS NCDDDDQPAL AEIERKNASM 780
  781 DDDEDDGMSS AVSAASALGQ SLTPAAQEMA LVSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..120] MSA 1.046977 View MSA. No confident structure predictions are available.
    2 View Details [121..325] MSA 2.166995 View MSA. No confident structure predictions are available.
    3 View Details [326..413] PSI-BLAST 52.522879 No description for 2v8qE was found.
    4 View Details [414..568] PSI-BLAST 5.0 No description for 2j9lA was found.
    5 View Details [569..633] PSI-BLAST 22.221849 No description for 2uv4A was found.
    6 View Details [634..814] PSI-BLAST 17.69897 Crystal Structure of GuaC (BA5705) from Bacillus anthracis at 1.8 A Resolution


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle